We present results derived from continuous and localized 35 keV (55)Mn(+) ion implantations into ZnO. Localized implantations were carried out by using self-ordered alumina membranes as masks leading to ordered arrays of implanted volumes on the substrate surfaces. Defects and vacancies in the small implantation volumes of ZnO were generated due to the implantation processes besides the creatio...

Influenza viral passaging through pre-vaccinated mice shows that emergent antigenic site mutations on the viral hemagglutinin (HA) impact host receptor-binding affinity and, therefore, the evolution of fitter influenza strains. To understand this phenomenon, we computed the Significant Interactions Network (SIN) for each residue and mapped the networks of antigenic site residues on a representa...

UNLABELLED The prevalence of autism spectrum disorders in epilepsy is approximately 15%-47%, with previous research by Wakeford and colleagues reporting higher autistic traits in adults with epilepsy. The aim of this study was to investigate autistic characteristics and their relationship to having seizures by employing two behavioral assessments in two samples: adults with epilepsy and control...

Experience with one’s native language(s) alters the way that speech is perceived from early in infancy. The effects of language input are clearly illustrated in a development process termed phonetic attunement, where declines in perceiving non-native phonetic contrasts, and facilitation in perceiving native ones begin to emerge in the first year of life (Best, McRoberts, & Goodell, 2001; Kuhl e...

1. Robert Koch Institut (RKI), Berlin, delegated to Bavarian Health and Food Safety Authority (LGL), Oberschleissheim, Germany 2. Postgraduate Training for Applied Epidemiology (PAE, German Field Epidemiology Training Program, FETP), Germany 3. Institut de Veille Sanitaire (French National Institute of Health, InVS), Paris, France 4. European Training Programme for Intervention Epidemiology (EP...

From measurements over the last two years we have demonstrated that the charge collection system based on Faraday cups can robustly give near-1% absolute implantation fluence accuracy for our electrostatically scanned 200 kV Danfysik ion implanter, using four-point-probe mapping with a demonstrated accuracy of 2%, and accurate Rutherford backscattering spectrometry (RBS) of test implants from o...

Polycomb-group (PcG) proteins mediate repression of developmental regulators in a reversible manner, contributing to their spatiotemporally regulated expression. However, it is poorly understood how PcG-repressed genes are activated by developmental cues. Here, we used the mouse Meis2 gene as a model to identify a role of a tissue-specific enhancer in removing PcG from the promoter. Meis2 repre...

Systems that can regulate and coordinate the expression of multiple enzymes for metabolic regulation and synthesis of important drug intermediates are poorly explored. In this work, a strategy for constructing a tunable multi-enzyme-coordinate expression system for biosynthesis of chiral drug intermediates was developed and evaluated by connecting protein-protein expressions, regulating the str...

Let ξ0, ξ1, . . . , ξω−1 be observations from the hiddenMarkov model with probability distribution P θ0 , and let ξω, ξω+1, . . . be observations from the hidden Markov model with probability distribution P θ1 . The parameters θ0 and θ1 are given, while the change point ω is unknown. The problem is to raise an alarm as soon as possible after the distribution changes from P θ0 to P θ1 , but to a...

The heavier alkali-metal monosulfides (KS, RbS, CsS, and FrS) have been studied by high-level ab initio calculations. The RCCSD(T) method has been employed, combined with large flexible valence basis sets. All-electron basis sets are used for potassium and sulfur, with effective core potentials being used for the other metals, describing the core electrons. Potential-energy curves are calculate...