Acute catecholamine cardiomyopathy is an uncommon, life-threatening manifestation of pheochromocytoma. The massive release of catecholamines from the adrenal medulla and their toxic effects on the coronary vessels and the cardiac myocytes play a significant role in the pathogenesis of cardiomyopathy in patients with pheochromocytoma. Severe manifestations, such as acute catecholamine cardiomyop...

Rapid cyclic fluctuations of blood pressure in patients with a pheochromocytoma have rarely been reported. The suitable conditions to induce this phenomenon are not adequately known. We report here a patient with an adrenal pheochromocytoma who showed this phenomenon after oral administration of labetalol.

A 46-year-old man presented with shock and adult respiratory distress syndrome. Investigations revealed an adrenal mass that was diagnosed, by fine-needle aspiration biopsy, as pheochromocytoma. Because biopsy is contraindicated in patients with pheochromocytoma, this confusing presentation underscores the value of excluding this diagnosis by biochemical means before performing fine-needle aspi...

High somatostatin receptor expression on the cell membrane of succinate dehydrogenase mutation-related pheochromocytoma and paraganglioma provides a potential target for imaging and therapy. (68)Ga-DOTATATE positron emission PET/CT may represent a new gold standard for staging pheochromocytoma/paraganglioma and have future therapeutic implications.

BACKGROUND Hypertension is the most common medical complication of pregnancy. Pheochromocytoma in pregnancy is rare, and if unrecognized, can cause serious perinatal morbidity and mortality. METHODS A patient with severe hypertension, postpartum pulmonary edema, and a recognized pheochromocytoma is described. RESULTS Abdominal palpation after vaginal childbirth reproduced the diagnostic tri...

Pheochromocytomas and paragangiomas are a class of neuroendocrine tumors with a widely variable clinical presentation ranging from paroxysmal episodes of critically elevated blood pressure to no clinical symptoms. Genetic predisposition to pheochromocytomas is well documented. Initial workup entails biochemical evaluation of urine catecholamine metabolites, intravenous contrast enhanced anatomi...

Malignant pheochromocytoma is a neuroendocrine tumor that originates from chromaffin tissue. Although osseous metastases are common, metastatic dissemination to the spine rarely occurs.Five years after primary diagnosis of extra-adrenal, abdominal pheochromocytoma and laparoscopic extirpation, a 53-year old patient presented with recurrence of pheochromocytoma involving the spine, the pelvis, b...

Currently, the only reliable indicator of malignancy in pheochromocytoma is the presence of distant metastasis or extensive local invasion; predicting behavior of pheochromocytoma remains challenging. We aimed to correlate the behavior of pheochromocytoma with its expression of nm-23, cyclooxygenase (COX)-2, and galectin-3 (genes used to predict the course of some neoplastic diseases), evaluate...

pheochromocytoma is a rare disease. a retrospective study of the signs and clinical course of this disorder was performed by evaluating medical records. our fidings indicate that the prevalence of pheochromocytoma was equal in men and women, and most patients (56%) were in their second and third decades of life. in 10% of the cases, the disease was bilateral, and in 13% it was outside the adren...