in the present study, a comprehensive and systematic strategy was described to evaluate the performance of several three-way calibration methods on a bio-analytical problem. parallel factor analysis (parafac), alternating trilinear decomposition (atld), self-weighted alternating trilinear decomposition (swatld), alternating penalty trilinear decomposition (aptld) and unfolded partial least squa...

a stability indicating high-performance liquid chromatography (hplc) method wasvalidated and used to study the degradation of cetirizine dihydrochloride in acidic and oxidativeconditions. the separation was carried out on a symmetry c18 column and a mixture of 50 mmkh2po4 and acetonitrile (60:40 v/v, ph = 3.5) was used as the mobile phase. the method waslinear over the range of 1-20 μg/ml of ce...

background: cattle can be considered as an important source for herbicides through nutrition. therefore, herbicide residue in animal products is a potential human exposure to herbicides causing public health problems in human life. triazines are a group of herbicides primarily used to control broadleaf weeds in corn and other feed ingredients and are considered as possible human carcinogens. to...

conclusions examination of the fasting lipid profile has clinical importance in predicting the efficacy of peg-ifn-α-2b plus rbv combination therapy for patients with hcv g1b even after the discovery of the il28 genotype as a potent predictive factor. objectives to re-examine the significance of lipoprotein profiles on virological response to peg-ifn plus rbv combination therapy in patients wit...

background: aflatoxin m1 (afm1) is a toxic compound that could be found in milk and dairy products. afm1 is the principle hydroxylated derivative of aflatoxin b1 (afb1), formed in liver and excreted into the milk in the mammary glands of both human and lactating animals that have been fed with afb1 contaminated diet. to the best of our knowledge, there is no report on stability of afm1 during p...

Two UV-spectrophotometric and one reverse phase high performance liquid chromatography methods have been developed for the simultaneous estimation of amlodipine besilate, losartan potassium and hydrochlorothiazide in tablet dosage form. The first UV spectrophotometric method was a determination using the simultaneous equation method at 236.5, 254 and 271 nm over the concentration range 5-25, 10...

Studies have been performed to investigate the effect of an ionic liquid, 1-butyl-3-methylimidazolium tetrafluoroborate, as mobile-phase modifier on the retention behaviour of N-carbobenzyloxy-D-phenylalanine and D-tryptophan on a reversed-phase silica-based column. Retention of these amino acids was determined with water–acetonitrile mobile phases and with mobile phases containing 2, 5, or 10 ...

■ CONTENTS Principles of Single Molecule Spectroscopy and Instrumental Techniques 84 General Considerations and Sample Requirements 84 Confocal Microscopy 85 Total Internal Reflectance Fluorescence Wide Field Imaging and Analysis 86 Chromatography Methods Studied by Single Molecule Spectroscopy 87 Reverse Phase Liquid Chromatography 87 Silica Surfaces: Normal Phase Chromatography and Capillary ...