In this study, a new reaction system for quantitative determination of ascorbic acid was introduced. The developed method is based on inhibitory effect of ascorbic acid on the Orange G-bromate system. The change in absorbance was followed spectrophotometrically at 478 nm. The dependence of sensitivity on the reaction variables including reagents concentration, temperature and time was investiga...

Counterfeit pharmaceutical products are a real threat to the health of patients, and to the reputation and commercial success of legitimate producers of genuine products. NIR chemical imaging provides a rapid method for detecting and comparing suspected counterfeit products with no sample preparation. With appropriate choice of operating conditions, multiple samples can be compared simultaneous...

Introduction: Given the growing prevalence of obesity in industrial societies including Iran, there is a growing demand for herbal weight loss drugs. Taking into account the heavy advertisements to sell the capsule as an herbal medicine, the present study was conducted in 2012 to determine the effective substance of prevalent super slim weight loss capsule. Methodology: ­Twenty-six super slim c...

BACKGROUND Asthma as a chronic health condition can be controlled when in addition to clinical care, adequate education and support is provided to enhance self-management. Like many other chronic health conditions improved self-management positively impacts the health-related quality of life (HRQoL). It can therefore be said that a well-structured pharmaceutical care delivery that addresses the...

Drug samples commonly are provided by physicians to patients in the outpatient setting. The use of drug samples, however, has come under scrutiny as critics argue that the practice is a marketing tool for the pharmaceutical industry. An additional problem facing the medical community is the growing rate of medication errors. Recently, there has been a national call for new methods of identifyin...

The relationship between the pharmaceutical industry and physicians is evermore complex and has called attention on both sides. It is evident that, for many, medical ethics, both in dealings and empathy with patients as with the relationship between the pharmaceutical industry and the government, which in their current state are undesirable. Therefore, there is an urgent need for guidelines tha...

Pharmaceutical residues are environmental contaminants of recent concern and the requirements for analytical methods are mainly dictated by low concentrations found in aqueous and solid environmental samples. In the current article, a review of the liquid chromatography-tandem mass spectrometry (LC-MS/MS) based methods published so far for the determination of pharmaceuticals in the environment...

Febuxostat FEB was determined by differential pulse “DP” adsorptive stripping voltammetry and hanging mercury drop electrode. In 0.04 mol L Britton-Robinson buffer solution, pH 10, an irreversible electrochemical reaction took place at about -350 mV, and the peak current was linearly varied over the concentration range of 12.5-200 ng mL FEB, with correlation coefficients of 0.9995, after 60 s a...

Ion-associate complexes of Itopride hydrochloride with zinc(II) thiocyanate, sodium cobaltinitrite and ammonium reineckate are precipitated. The solubility of the ion associates at the optimum pH and ionic strength values have been examined. Saturated solutions were prepared at different temperatures ( 25 – 60C ) under the optimum precipitation conditions and the metal ion contents ( zinc, chro...

Zinc ions form a yellow complex with di-2-pyridyl ketone salicyloylhydrazone (DPKSH). This complex showed maximum absorption at 376 nm, and it was used to develop spectrophotometric flow injection methods for Zn(II) determination in different samples. Two types of flow systems were proposed. In the first system, a linear analytical curve was obtained in a concentration range from 0.217 to 4.60 ...