Molecular imaging has witnessed a tremendous change over the last decade. Growing interest and emphasis are placed on this specialized technology represented by developing new scanners, pharmaceutical drugs, diagnostic agents, new therapeutic regimens, and ultimately, significant improvement of patient health care. Single photon emission computed tomography (SPECT) and positron emission tomogra...

UNLABELLED We report the extended application of an automated computer technique for three-dimensional spatial registration of SPECT and PET studies. METHODS The technique iteratively reslices a misaligned data set until the sum of the absolute differences (SAD) from a reference data set is minimized. The registration accuracy was assessed in Hoffman brain phantom studies collected with known...

Radioembolization (RE) with glass microspheres (MS) loaded Yttrium-90 (90Y) has been used to treat tumors in the liver some reported success. However, assessing absorbed doses (AD) planning tumor volume (PTV) and normal (NLV) is a key problem address RE. In clinical practice, computation of 90Y activity be administered follows manufacturer’s recommendations, which do not consider specific chara...

Technological Educational Institute of Athens, Greece The contributions of the present European Journal of Nuclear Medicine and Molecular Imaging Physics Proceedings issue “PSMR2014 – 3 International Conference on PET-MR and SPECT-MR” give a representative overview of oral and poster presentations at the third Conference on PET-MR and SPECT-MR. PSMR2014 took place in Kos Island (Greece) in May ...

UNLABELLED With an increasing emphasis on quantitation of SPECT imaging and its use in dosimetry to guide therapies, it is desirable to understand the repeatability in normal-organ SPECT uptake values (SPECT-UVs). We investigated the variability of normal abdominal organ uptake in repeated (111)In-pentetreotide SPECT studies. METHODS Nine patients with multiple (111)In-pentetreotide SPECT/CT ...

A cintilografia de perfusão miocárdica (CPM) com tomografia computadorizada por emissão fóton único (SPECT) é importante para o diagnóstico e avaliação prognóstica em pacientes doença arterial coronariana (DAC). CPM avalia a presença, extensão grau isquemia e/ou infarto geralmente meio observação visual ou parâmetros semiquantitativos. Apesar seus valores prognóstico comprovados, natureza relat...

Expectation Maximization iterative reconstruction algorithms are being widely used in PET and SPECT imaging. The system probability matrix is usually calculated by using Monte Carlo simulations, since the analytical calculation is a rather complicated problem, especially in 3D reconstruction; however, realistic Monte Carlo simulations in 3D are time consuming and simplifications are necessary. ...

A clinical prototype of combined Combined Positron Emission Tomography (PET) / Computed Tomography (CT) system went under the clinical evaluation in 1998. After three years of research and clinical evaluation first clinical combined PET/CT system was installed in a clinic in 2001 [1-3]. Gradually clinical utilization of combined PET/CT increased tremendously particularly in oncological imaging ...