1Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI 48109-1078, USA 2LoB5 Research Unit, School of Dentistry & Research Center for Biomineralization Disorders, Chonnam National University, Gwangju 500-757, Republic of Korea 3Department of Stomatology, Implantology and Dental and Maxillofacial Radiology, School of Dental Medicine, University o...

1Department of Oral Biology, School of Dentistry, Creighton University, Omaha, NE 68178, USA 2Preclinical Program, College of Dental Medicine-Illinois, Midwestern University, 555-31st Street, 102 Redwood Hall, Downers Grove, IL 60515, USA 3Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA 4Oral and Maxillofacial Surgery, School o...

Department of Periodontics, University of Pennsylvania, Philadelphia, PA, USA Department of Oral Basic & Clinical Sciences, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia Department of Orthopedics, University of Medicine and Dentistry of New JerseydGraduate School of Biomedical Sciences, Newark, NJ, USA Department of Biochemistry and Molecular Biology, University of Medic...

systemic antibiotics in conjunction with scaling and root planing (srp), can offer an additional benefi t over srp alone in the treatment of periodontitis, in terms of clinical attachment loss (cal) and pocket depth change, and reduced risk of additional cal loss. however, antibiotics are not innocuous drugs. their use should be justifi ed on the basis of a clearly established need and should n...