The aim of this study was to compare potential aspects of periapical lesion formation in hypertensive and normotensive conditions using hypertensive (BPH/2J) and wild-type control (BPN/3J) mice. The mandibular first molars of both strains had their dental pulp exposed. At day 21 the mice were euthanized and right mandibular molars were used to evaluate the size and phenotype of apical periodont...

The purpose of this study was twofold: first, to determine the influence on the healing of the periapical tissues when selected bacterial strains and combinations thereof remain after root canal treatment; and, second, the relationship to healing of the quality of the root filling. In eight monkeys, 175 root canals, previously infected with combinations of four or five bacterial strains and wit...

This study was performed to evaluate radiographic healing of teeth with apical periodontitis, treated in one visit or in two visits (a) with or (b) without calcium hydroxide as an intracanal disinfecting medicament. The patients were assigned one of the three treatment groups by the throwing of a die. The Periapical Index (PAI) Scoring Method was used to compare differences in periapical status...

The study involved 300 elderly patients with chronic periapical periodontitis. The patients were randomly assigned into three groups. The treatment for group A used a Mtwo Ni-Ti rotary instrument combined with ultrasonic irrigation of a 2.5% NaOCl solution. The group B used the same instrument combined with ultrasonic irrigation of an active silver ion antibacterial solution. The group C used t...

Cemento-osseous dysplasia is a disorder typically found in middle-aged black women. However, the present report describes a case in a 61-year-old Vietnamese male. Without proper pulp testing and diagnosis, the radiographic presentation can easily be misdiagnosed as periapical periodontitis. On the basis of pulp vitality, lack of clinical symptoms and radiographic features, the diagnosis in this...

Two cases are reported in which incomplete placement of 4 mm mineral trioxide aggregate (MTA) plug was performed unintentionally at the apical third of permanent immature teeth with open apex and apical periodontitis. As confirmed radiographically, there were gaps between MTA and dentinal walls along the MTA-dentin interface. After setting of MTA was confirmed, endodontic treatment was complete...

Nowadays, the bactericidal effect of laser irradiation is well known in endodontic therapy. Many studies showed that, in combination with an appropriate shaping and cleaning of root canal system, laser irradiation, inside the root canal, could increase the percentage of bactericidal effect in endodontic treatment. Three clinical cases of teeth with periapical chronic periodontitis are presented...

BACKGROUND Apical Periodontitis (AP) is an inflammatory disease that affects the tissues surrounding the root end of a tooth. The disease which is caused by endodontic infections presents in different clinical ways including development of an acute abscess. Recent studies have provided information suggesting role of a multitude of factors in pathogenesis of acute apical abscess (AAA). In this c...

PURPOSE The purpose of this clinical feasibility study was to evaluate the applicability of magnetic resonance imaging (MRI) for the assessment of apical periodontitis in direct comparison with cone beam CT (CBCT). MATERIALS AND METHODS 19 consecutive patients (average age 43 ± 13 years) with 34 lesions in total (13 molars, 14 premolars and 7 front teeth) were enrolled in this feasibility stu...

The polymerase chain reaction (PCR) is an elegant technology for faithfully replicating and amplifying the master molecule of life, but a valid scientific procedure remains essential without which the resulting data have only very limited value. The presence of microbial infection in the complex apical root canal system is the major cause of posttreatment apical periodontitis in well-treated te...