Periapical lesions are diseases resulting from contamination and necrosis of dental pulp and the progression of this infection toward the periapical tissues. Technological advances in microbiological culture and identification have shown that anaerobic microorganisms, especially Gram-negative, are predominate in root canals of teeth with pulp necrosis and chronic periapical lesions. Gram-negati...

Background and Aim: To compare the radiographic distance from the inferior part of mandibular second and third molars to the superior border of mandibular canal on radiographs obtained by conventional periapical radiographs, intraoral photostimulable phosphor plate (Intraoral PSP) and panoramic photostimulable phosphor plate (Panoramic PSP). Subjects and Methods: The study was carried out on 25...

statement of problem: failure of endodontic treatment is determined on the basis of radiographic findings and clinical signs and/ or symptoms of the treated teeth. purpose: the purpose of this study was to determine endodontic treatment failure in relation to various factors influencing it in teeth with periapical lesions (clinically and radiographically). materials and methods: teeth which had...

Stem cells are the pluripotent cells that have the capacity to differentiate into other specialized cells. Recently, many experiments have been conducted to study the potentiality of stem cells in the tissue regeneration. We report two cases treated utilizing stem cells from human exfoliated deciduous teeth (SHED) in the management of periapical lesions in permanent teeth. Two normal human deci...

The objective of this study was to evaluate bacterial prevalence in 31 root canals of human deciduous teeth with necrotic pulp and periapical lesions using bacterial culture. After crown access, the material was collected using absorbent paper points for microbiological evaluation and determination of colony forming units (CFU). Anaerobic microorganisms were found in 96.7% of the samples, black...

AIM The aim of the present study was to identify periapical changes 20-27 years after root-canal treatment. METHODOLOGY The periapical condition of 265 roots filled by undergraduate students was evaluated in two series of intraoral radiographs taken 10-17 and 20-27 years after treatment. Roots (72) not recorded with a normal periapical situation on both occasions by two observers, were re-eva...

The epithelial proliferation associated with inflammatory periapical lesions and with periapical cyst formation represents an interesting but poorly understood pathological change. Keratinocyte growth factor (KGF) is a recently identified growth factor that is produced by stromal fibroblasts and acts specifically to stimulate epithelial growth and differentiation. To investigate its possible ro...

Periapical bone loss is one of the prominent pathological and clinical features of periapical periodontitis. Previous studies have demonstrated that follicle‑stimulating hormone (FSH) could directly affect skeletal remodelling by stimulating the formation and the function of osteoclasts in vitro and in vivo. However, the effect of FSH on periapical bone loss remained to be fully elucidated. In ...