Background: Hypothermic perfusion can be used as adjunctive therapy to reduce corneal endothelial cell damage during phacoemulsification procedures. This study aims evaluate the effect of hypothermic on expression Superoxide Dismutase-1 (SOD1) and morphological changes in endothelium after ultrasound energy exposure. Methods: Sixteen New Zealand white rabbits (n=16 eyes) were randomly divided i...

Objective: Measurement of blood-brain permeability dysfunction in active and chronic MS lesions with T1-weighted dynamic contrast-enhanced MRI to show variation in inflammatory activity Background: blood-brain-barrier perfusion characterization impaired in MS as some studies have shown recently buta comparison between perfusion parameters in contrast-enhanced and non-enhanced lesions not have ...

BACKGROUND Brain perfusion is altered in both alcohol dependence and stimulant dependence. Although most substance users also abuse/depend on alcohol concurrently (polysubstance users; PSU), rigorous perfusion research in PSU is limited. Also, the relationships of perfusion abnormalities with cognition, impulsivity, or decision making are not well known. METHODS Arterial spin labeling MRI and...

The relationship between cardiac output (CO) and peripheral resistance (Rp) was examined under the following conditions for coronary perfusion: constant coronary flow perfusion; perfusion with a pressure equal to mean aortic pressure (AoP perfusion); and perfusion with a pressure equal to the mean AoP 30 mm Hg (AoP 30 mm Hg perfusion). We also examined the coronary pressure-flow relationship. F...

The aim of this article is to describe a novel hardware perfusion phantom that simulates myocardial first-pass perfusion allowing comparisons between different MR techniques and validation of the results against a true gold standard. MR perfusion images were acquired at different myocardial perfusion rates and variable doses of gadolinium and cardiac output. The system proved to be sensitive to...

OBJECTIVE Peripheral perfusion in critically ill patients frequently is assessed by use of clinical signs. Recently, the pulse oximetry signal has been suggested to reflect changes in peripheral perfusion. A peripheral perfusion index based on analysis of the pulse oximetry signal has been implemented in monitoring systems as an index of peripheral perfusion. No data on the variation of this in...

this study evaluated the relationship between the location of the most severe coronary artery stenosis and the subsequent acute myocardial infarction (ami). methods: of 1590 patients who were admitted with a diagnosis of ami, we identified 44 patients who had undergone previous myocardial perfusion spect. thirty-one of these patients also had previous coronary angiography. the relationship betw...