Here we genetically characterise pelvic finless, a naturally occurring model of hindlimb loss in zebrafish that lacks pelvic fin structures, which are homologous to tetrapod hindlimbs, but displays no other abnormalities. Using a hybrid positional cloning and next generation sequencing approach, we identified mutations in the nuclear localisation signal (NLS) of T-box transcription factor 4 (Tb...

Kalevi J. A. Kairemo, Antti P. Jekunen, and Mikko Tenhunen Department of Clinical Chemistry, Helsinki University Central Hospital, FIN-00029, Finland 2 Department of Clinical Pharmacology, Helsinki University Central Hospital, FIN-00029, Finland 3 Department of Oncology, Helsinki University Central Hospital, FIN-00029, Finland ____________________________________________________________________...

a Galilaeus Oy, P.O. Box 113, FIN-20781 Kaarina, Finland. E-mail: [email protected]; Fax: 358-2-2731460; Tel: 358-2-2741450 b Structural Chemistry Group, Department of Chemistry, University of Turku, Vatselankatu 2, FIN-20014 Turku, Finland c Departamento de Biologia Funcional e Instituto, Universitario de Biotecnologia de Asturias, ESP-33006 Oviedo, Spain d Department of Biochemistry, ...

Thin perforated Steel Plate Shear (SPS) Walls are among the most common types of energy dissipating systems. The applied holes reduce the shear strength of the plate and allow to decrease the profile size of the members at the boundary of the panel when these systems are used in the typical design of structures. On the other hand, the different fracture locations of these panels are visible whe...

In the present work, the performance of the particle swarm optimization and the genetic algorithm compared as a typical geometry design problem. The design maximizes the heat transfer rate from a given fin volume. The analysis presumes that a linear temperature distribution along the fin. The fin profile generated using the B-spline curves and controlled by the change of control point coordinat...

Adipose fins are found on approximately 20% of ray-finned fish species. The apparently rudimentary anatomy of adipose fins inspired a longstanding hypothesis that these fins are vestigial and lack function. However, adipose fins have evolved repeatedly within Teleostei, suggesting adaptive function. Recently, adipose fins were proposed to function as mechanosensors, detecting fluid flow anterio...

This study explores the use of teaching-learning-based optimization (TLBO) algorithm for thermodynamic optimization of a plate-fin heat exchanger. Minimizing the total number of entropy generation units for specific heat duty requirement under given space restrictions is considered as objective function. Based on the applications heat exchanger length, fin frequency, numbers of fin layers, lanc...

A new species of Lycengraulis from the Amazon basin is described. Lycengraulis figueiredoi can be distinguished from L. grossidens by a short upper maxilla, its posterior margin not reaching the lower maxilla joint (vs. upper maxilla longer, its posterior margin reaching to or a little past of mandible joint). Lycengraulis figueiredoi can be distinguished also from L. poeyi by 26 to 31 anal-fin...

Effects of the number of fins, fin pitch and wind velocity on air-cooling were investigated using experimental cylinders for an air-cooled engine of a motorcycle. Experimental cylinders that had a various number of fins and fin pitches were tested in a wind tunnel. Then the temperature inside of the cylinder, on the surface of the fins and in the space between the fins was measured. Results ind...

This study investigated the effect of the installation of flood dams on the morphological variation of Alburnoides samiii Mousavi-Sabet, Vatandoust & Doadrio, 2015, in Toolkhone River, origin from Somam Mountain, the South Caspian Sea basin, north of Iran. Multivariate analysis (MANOVA) was employed for morphometric characteristics of the fish inhabit upstream and downstream of the dams. Signif...