Despite the introduction of new antifungal agents, resistances to antifungal therapy continue to increase and outcome of invasive fungal infections treatment is frequently suboptimal. A large amount of the recent effort in antifungal drug discovery has focused on a limited set of targets with functions known or expected to be important for fungal viability and virulence. A variety of techniques...

Abstract Increasing job duties and responsibilities associated with the changing role of school principals have prompted even greater accountability. As a result, are faced competing demands expectations in various forms accountability from multiple stakeholders. This study examines principals’ perception context work intensification particular focus on question “accountable to whom why.” A tot...

Introduction: Recognition of professional and unprofessionalbehaviors is the most important and fundamental factor whichaffects the relationships between the doctors and patients.Therefore, in order to progress in their professional life, doctorsare supposed to understand and follow these behaviors.Methods: This is a cross-sectional, descriptive analytical study.All students in teaching hospita...

due to his nature, man always asks questions about the meaning of things. all branches of knowledge and civilization are the answers he has given to the mystery of being, of his own and of other things. here, the question about the meaning of action is also considerably important. in this study, we are going to analyze the answers given from a sociological view to the question about the meaning...

A Digital Microfluidic Biochip (DMFB) offers a promising platform for medical diagnostics, DNA sequencing, Polymerase Chain Reaction (PCR), and drug discovery and development. Conventional Drug discovery procedures require timely and costly manned experiments with a high degree of human errors with no guarantee of success. On the other hand, DMFB can be a great solution for miniaturization, int...

Let (* ) u,, du + q(x, t) u = 0 in D x [0, T], where D c R3 is a bounded domain with a smooth boundary dD, T> d, d: =diam D, q(x, I) E C( [O, 2’1, L”(D)). Suppose that for every (**) ~I,+~=f(x, l)EC’(dDx [0, T]), the value u*,;,:= h(s, t) is known, where N is the outer normal to dD, u solves (* ) and ( ** ) and satisfies the initial conditions u = U, = 0 at I = 0. Then q(x, I) is uniquely deter...

There are well-known constructions of the exceptional simple Lie algebras of type E8 and F4 which go back to Witt [Wit41], as Z2-graded algebras g = g0̄⊕g1̄ with even part the orthogonal Lie algebras so16 and so9 respectively, and odd part given by their spin representations (see [Ada96]). Brown [Bro82] found a new simple finite dimensional Lie algebra over fields of characteristic 3 which presen...