[ 142 ] Georg Christoph Lichtenberg’s reference to “a knife without a blade, for which the handle is missing” has been illustrated recently by Broomberg and Oliver Chanarin (1). In his work, Jokes and their Relation to the Cognitive Unconscious, Freud suggested that the “knife without a blade which has no handle” is as absurd or funny as a “frame without a picture” (2). The joke is, of course, ...

In a 62-year-old man with medullary carcinoma of the thyroid, a postoperative Tc-99m dimercaptosuccinic acid [(V) DMSA] study was requested. In the Tc-99m (V) DMSA scan. no abnormalities, indicating local recurrence or metastatic disease, were observed. However, there was increased uptake in the spleen and liver and significantly diffusely increased uptake in the bone marrow. The patient also h...

I ntroduction of Haemophilus influenzae type B (HiB) containing pentavalent vaccines (a combination vaccine which protects against five killer diseases-diphtheria , pertussis, tetanus, hepatitis B and Haemophilus in-fluenzae type B) in the Universal Immunization Program (UIP) was a far sighted decision taken in 2009 by the Ministry of Health and Family Welfare, Government of India. This decisio...

The element phosphorus (P) controls growth in many ecosystems as the limiting nutrient, where it is broadly considered to reside as pentavalent P in phosphate minerals and organic esters. Exceptions to pentavalent P include phosphine--PH3--a trace atmospheric gas, and phosphite and hypophosphite, P anions that have been detected recently in lightning strikes, eutrophic lakes, geothermal springs...

BACKGROUND Limited data are available regarding topical and systemic therapies for Leishmania tropica in children. OBJECTIVE We sought to characterize the clinical presentation and evaluate the efficacy and safety of topical and systemic treatments in pediatric patients infected with L tropica. METHODS A retrospective study was performed on 47 children with L tropica cutaneous leishmaniasis...

Revision of crystal structure of the rare U-oxide mineral richetite provided crystallographic evidence for the presence of pentavalent U. The structure of richetite, space group P1, a = 12.0919(2), b = 16.3364(4), c = 20.2881(4) Å, a = 68.800(2), b = 78.679(2), g = 76.118(2)°, with V = 3600.65(14) Å3 and Z = 1, was solved by charge-flipping algorithm and refined to an agreement index (R) of 5.6...

described in Table 1 ranged from 2 to 16 months. Diagnosis was delayed due to the atypical presentation, and was usually established only after several medical visits. Treatment in most cases was with intramuscular pentavalent antimonials, given the tendency towards chronicity and the risk of deformity at the site of the lesion, although intralesional administration can also bring about complet...

Arsenic is noxious metal exist in water in form of organic dimethyl arsenic acid (C2H7AsO2) and monomethylarsonic acid (CH5AsO3) while in inorganic arsenic trioxide (As2O3) and sodium arsenate (NaH2AsO4). Its trivalent and pentavalent forms are abundant in natural water. Its trivalent form is 60 times more hazardous than pentavalent form. Reports proved that arsenic contamination in water is th...

Parenteral pentavalent antimonials remain the standard therapy for cutaneous leishmaniasis. More effective and patient-compliant topical treatments are an important alternative treatment for the localized self-limiting forms of this disease. Two paromomycin ointments are commercially available but their use is limited by either toxicity or lack of efficacy. Other topical formulations have been ...

Background Vaccination coverage levels fall short of the Global Vaccine and Action Plan 90% target in low- middle- income countries (LMICs). Having identified traditional religious leaders (TRLs) as potential public health change agents, this study aimed at assessing effect training them to support routine immunisation for purpose improving uptake childhood vaccines Cross River State, Nigeria. ...