نتایج جستجو برای: pegylation

تعداد نتایج: 824  

Journal: :Bioorganic & medicinal chemistry letters 2013
Solène Passemard Davide Staedler Lucia Učňová Guillaume Stéphane Schneiter Phally Kong Luigi Bonacina Lucienne Juillerat-Jeanneret Sandrine Gerber-Lemaire

A straightforward route is proposed for the multi-gram scale synthesis of heterobifunctional poly(ethylene glycol) (PEG) oligomers containing combination of triethyloxysilane extremity for surface modification of metal oxides and amino or azido active end groups for further functionalization. The suitability of these PEG derivatives to be conjugated to nanomaterials was shown by pegylation of u...

2013
Peter Yu Deanna Hurum Jinyuan Wang Terry Zhang Jeffrey Rohrer

Background: Pancreatic islet transplantation is one of the most promising strategies for treating patients with type I diabetes mellitus.Objective: We aimed to assess the immunoisolation properties of the multilayer encapsulated islets using alginate-chitosan-PEG for immunoprotection and insulin secretion from the encapsulated islets induced under differe...

2014
Ashish Ranjan Sharma Shyamal Kumar Kundu Ju-Suk Nam Garima Sharma C George Priya Doss Sang-Soo Lee Chiranjib Chakraborty

Proteins and genes of therapeutic interests in conjunction with different delivery systems are growing towards new heights. "Next generation delivery systems" may provide more efficient platform for delivery of proteins and genes. In the present review, snapshots about the benefits of proteins or gene therapy, general procedures for therapeutic protein or gene delivery system, and different nex...

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