Since 1969 the International Atomic Energy Agency and the World Health Organization (along with the Pan American Health Organization, working with countries in Latin America and the Caribbean) have operated postal dosimetry audits based on thermoluminescent dosimetry (TLD) for radiotherapy centers. The purpose of these audits is to provide an independent dosimetry check of radiation beams used ...

A method is described for computing patient-specific absorbed dose rates to active marrow which accounts for spatial variation in bone volume fraction and marrow cellularity. A module has been added to the 3D Monte Carlo dosimetry program DPM to treat energy deposition in the components of bone spongiosa distinctly. Homogeneous voxels in regions containing bone spongiosa (as defined on CT image...

It is the purpose of this study to evaluate how self-expanding stents (SESs) affect esophageal cancer radiation planning target volumes (PTVs) and dose delivered to surrounding organs at risk (OARs). Ten patients were evaluated, for whom a SES was placed before radiation. A computed tomography (CT) scan obtained before stent placement was fused to the post-stent CT simulation scan. Three method...

Nowadays we medical physicists are bombarded with guidelines and task reports, and we may see similar ones from different organizations in the United States of America or worldwide. Many extraordinary and diligent medical physicists have devoted their time and knowledge in creating these documents. Yet some of us might be wondering: should we optimize the use of our resources by establishing a ...

UNLABELLED Clinical PET of apoptosis may have substantial value in advancing patient care. We report here the first-in-humans study with (18)F-labeled 2-(5-fluoropentyl)-2-methyl malonic acid ((18)F-ML-10), a small-molecule PET tracer for apoptosis. Presented are the dosimetry, biodistribution, stability, and safety profiles of this PET tracer in healthy human volunteers. Also reported is trace...

Abstract The theranostic concept to use diagnostic and therapeutic nuclides image treat cancer was established many years ago for thyroid disease. With the success of [ 177 Lu]-labeled agents targeting neuroendocrine tumors or prostate cancer, interest this has been significantly rising. possibility localize quantify a target within patient opens up novel possibilities, but also challenges sele...

amount of 177Lu for every cycle? Although this is now the standard approach, it is reasonable to ask whether advantages might accrue to administering different amounts of radioactivity at different treatment cycles. Kulkarni et al. from the Zentralklinik Bad Berka (Germany) reported on “Serial dosimetry during 177Lu-PSMA radioligand therapy in the same patient” [316]. The authors performed dosi...

INTRODUCTION In radiation therapy centers across Iran, protection of normal tissues is usually accomplished by either Cerrobend or lead block shielding. In this study, the influence of these two shielding methods on central axis dose distribution of photon beam a Cobalt unit was investigated in clinical conditions. MATERIALS AND METHODS All measurements were performed for 60Co γ-ray beams and...