Background: A large proportion of patients presenting with lumbar disc disease are opium addicts in our region. It was, therefore, hypothesized that morphine might affect the intervertebral disc. We investigated the histological findings of morphine dependency on intervertebral discs in rat. Methods: Forty NMRI adult male rats (230-250 g) placed on ordinary diet and received aqueous solution of...

Background: Cervical spondylosis is a degenerative process involving changes in soft tissue and bone of intervertebral discs. Objective: To evaluate wrestling induced cervical spondylosis. Methods: 83 male wrestlers with the age range of 15 to 55 were randomly studied against 79 non-wrestlers of the same age. Clinical and radiological assessments were carried out and recorded in both groups. Wr...

PURPOSE Changes in tumor metabolism from positron emission tomography (PET) in locally advanced breast cancer (LABC) patients treated with neoadjuvant chemotherapy (NC) are predictive of pathologic response. Serial dynamic [(18)F]-FDG (fluorodeoxyglucose) PET scans were used to compare kinetic parameters with the standardized uptake value (SUV) as predictors of pathologic response, disease-free...

Purpose: Changes in tumor metabolism from positron emission tomography (PET) in locally advanced breast cancer (LABC) patients treated with neoadjuvant chemotherapy (NC) are predictive of pathologic response. Serial dynamic [F]-FDG (fluorodeoxyglucose) PET scans were used to compare kinetic parameters with the standardized uptake value (SUV) as predictors of pathologic response, disease-free su...

Longitudinal change in five cognitive abilities was investigated to determine if the direction or magnitude of change was related to the individual's ability level. Adults between 18 and 97 years of age performed three versions of 16 cognitive tests on two occasions separated by an average of 2.7 years. In order to control for influences associated with regression toward the mean, level of abil...

Assessing cognitive change in older adults is a common use of neuropsychological services, and neuropsychologists have utilized several strategies to determine if a change is "real," "reliable," and "meaningful." Although standardized regression-based (SRB) prediction formulas may be useful in determining change, SRBs have not been widely applied to older adults. The current study sought to dev...

It is widely recognized that experience with cognitive tests can influence estimates of cognitive change. Prior research has estimated experience effects at the level of groups by comparing the performance of a group of participants tested for the second time with the performance of a different group of participants at the same age tested for the first time. This twice-minus-once-tested method ...

Does personality change across the entire life course, and are those changes due to intrinsic maturation or major life experiences? This longitudinal study investigated changes in the mean levels and rank order of the Big Five personality traits in a heterogeneous sample of 14,718 Germans across all of adulthood. Latent change and latent moderated regression models provided 4 main findings: Fir...

purpose: to report the clinico-pathological and ultrastructural features of a case of meesmann corneal dystrophy (mcd). case report: a 10-year-old boy presented with decreased vision in both eyes since early childhood. slitlamp biomicroscopy disclosed diffuse intraepithelial microcystic changes in the cornea but other layers appeared unremarkable. high pathologic myopia and amblyopia were other...