Pasteurella multocida is a rare cause of bacterial meningitis. A 56-year-old man with several pets developed a profoundly decreased level of consciousness following left tympanomastoidectomy. Lumbar puncture produced cerebrospinal fluid with the typical findings of meningitis (low glucose, high protein, high leukocytes). Cultures from the cerebrospinal fluid and a swab of the left ear revealed ...

A systematic analysis of the bacteriostatic/bactericidal effect of several antibiotics used in veterinary medicine was carried out by time-kill kinetic analysis using P. haemolytica, P. multocida, A. pleuropneumoniae, and E. coli. The antibiotics tested were enrofloxacin, danofloxacin, erythromycin, tilmicosin, penicillin G, ceftiofur and tetracycline. Unexpectedly, the antibiotics well charact...

in order to show the type and severity of gross and histopathologic lesions induce by vaccinal strain (serotype a1) of pateurella mulocida, ten four-week-old spf chickens were inoculated intramuscularly with 75 cfu of ( 0.5 ml of 10-7 dilution) bacterium. all birds died in less than 16 hours. no prominent gross lesions were observed in different organs. in microscopic examination, the most comm...

U.S. Appl. No. 10/767,441, filed Jan. 30, 2004, Pending. U.S. Appl. No. 11/372,187, filed Mar. 10, 2006, Pending. Carter, "Observations on the Pathology and Bacteriology of Shipping Fever in Canada", Can. J. Comp. Med., vol. 18, No. 10, pp. 359-364, 1954. Collier, "Significance of Bacteria in Bovine Respiratory Disease", A.V.M.A., vol. 153, No. 12, pp. 1645-1651, 1968. Schiefer, et al., "Correl...

Molecular typing of twenty-five Pasteurella multocida isolates has been assessed by restriction fragmentlength polymorphism (RFLP) of a species-specific PCR assay. Amplification was based on the gene ompH, encoding a major outer memberane protein. RFLP analysis of the 1.2 kb ompH-amplification usingEcoRI, HindIII and CfoI endonucleases produced 7 different patterns for the twenty fi...

Pasteurella multocida is responsible for one of the major animal diseases with economic importance in both developed and developing countries. P. multocida B:2 causes haemorrhagic septicemia (HS) in cattle and buffaloes, which result in heavy economic losses through direct effect, resulting in high mortality rates and indirect effects through impairment of the animal productivity. It is well kn...

Pasteurella multocida possesses various virulence factors, including capsule, lipopolysaccharide, fimbriae, toxins, outer membrane proteins, and adhesions. Adhesins have a crucial role in mediating colonization and invasion of the host. The aim of the present study was to identify the prevalence of adhesion factor genes and resistance/sensitivity patterns among the avian P. multocida isolates f...

Avian Pasteurella multocida is the causative agent of fowl cholera, a disease much affecting the poultry industry. In order to study the efficacy of the recombinant subunit vaccine constructed with ptfA gene of avian P. multocida, the ptfA gene fragment amplified by PCR from avian P. multocida was cloned into the prokaryotic expression vector pET32a and the recombinant plasmid pET32a-ptfA was o...

BACKGROUND Integrative and conjugative elements (ICEs) have not been detected in Pasteurella multocida. In this study the multiresistance ICEPmu1 from bovine P. multocida was analysed for its core genes and its ability to conjugatively transfer into strains of the same and different genera. METHODS ICEPmu1 was identified during whole genome sequencing. Coding sequences were predicted by bioin...

Four lines of turkeys, a randombred control (RBC2) started in 1966 and three sire lines (F, A, and B), were challenged with a field isolate of Pasteurella multocida (capsular serogroup A, somatic serotype 3, 4) at 6 wk of age. Line F, a subline of the RBC2 line, was selected for 28 generations for increased 16-wk BW and Lines A and B were primary breeding sire lines from two commercial breeders...