Parry-Romberg syndrome (PRS) is a rare, acquired disorder characterized by progressive unilateral facial atrophy of the skin, soft tissue, muscles, and underlying bony structures that may be preceded by cutaneous induration. It is sometimes accompanied by ipsilateral brain lesions and neurological symptoms. Here we present the case of a 10-year-old girl with right-sided PRS and recurrent monopl...

The article presents a clinical case of rare onset and special course juvenile scleroderma. A child who was born lives in the ecologically unfavorable industrial Donetsk region is described. literature review influence environment on morbidity features autoimmune pathology patients offered. In particular, indicates that negative environmental factors lead to an increase progression systemic scl...

BACKGROUND We reviewed the literature on published cases of progressive facial hemiatrophy (Parry-Romberg syndrome) to identify possible pathophysiological mechanisms of the syndrome. OBJECTIVE To describe the somatosensory phenotype of a previously unreported patient with progressive facial hemiatrophy and facial pain. DESIGN Case report and 4-month follow-up period. SETTING University-b...

We describe a case of a 50-year-old woman who developed drug-resistant status epilepticus with complex partial and secondary generalised seizures. She had suffered from Parry-Romberg syndrome (PRS) for more than 40 years. Right-sided progressive hemifacial atrophy (PHA) had begun at the age of 7 (figure 1A), followed by epilepsy at the age of 14 years. In the past 2–3 years before the latest ad...