A 46-year-old female with a history of muscle weakness, nephrolithiasis and peptic ulcer. She was found to have hypercalcemia (115 mg/l), hypophosphoremia (16 mg/l) and increased PTH serum level (1090 pg/l). In order to discriminate between PH and pseudohyperparathyroidism, a solid-phase, two site chemiluminescent enzyme-labeled immunometric assay directed towards the intact PTH molecule was us...

INTRODUCTION: HGF (Hepatocyte Growth Factor), TGFb1 (Transforming Growth Factor b1) and IGF-I (Insulin Like Growth Factor I) are cytokines that are involved in the parathyroid tumors formation and growth. We tried to determine, if there are changes and relationships in the production of these cytokines by tumor cells of parathyroid tumors. MATERIAL AND METHODS: We determined concentrations of H...

Parathyroid cyst is a very rare abnormality. The diagnosis can be made based on ultrasound and the analysis of the aspirated cystic fluid for parathyroid hormone (PTH). We report the case of a nonfunctional parathyroid cyst in a 50-year-old female patient with an anterior neck mass. The patient was complaining of pain in the anterior cervical region, dysphagia, dyspnea and dysphonia started thr...

Thyroparathyroidectomy of rats on a diet low in calcium reduces production of 1,25-dihydroxycholecalciferol from 25-hydroxycholecalciferol to negligible levels within 40 hr, and increases production of another metabolite, called Va. Parathyroid extract, at a dose of 20 units per day, prevents these changes. When 40 units per day of parathyroid extract is given 48 hr after thyroparathyroidectomy...

BACKGROUND Technetium-99m sestamibi scintigraphy has become one of the most popular techniques for localization of the parathyroid gland after failure of primary neck exploration. OBJECTIVE To examine the efficacy of sestamibi with the hand-held gamma ray detecting probe for the identification of parathyroid adenomas during revision parathyroidectomy. METHODS We reviewed six cases of probe-...

In short, the diagnosis ofDPB is usually difficult inmanypatients due to the non-specific clinical and radiological characteristics, in addition to the fact that it is not suspected due to its infrequency in Western countries. Nevertheless, it should be kept in mind when evaluating patients without a history of smokingwho present with exertional dyspnea, chronic productive cough, and tree-in-bu...

abstract background: primary hyperparathyroidism is autonomous production of parathyroid hormone. after removal of adenoma, one of the surgeons concern is postoperative hypocalcaemia. there is no precise method to determine if patients have hypocalcaemia postoperatively. the purpose of this study was to determine the relation between parathyroid adenoma weights, postoperative serum calcium and ...

Parathyroid lipoadenomas are a rare and benign variant of parathyroid adenomas that are defined morphologically by an abundance of adipocytes. The clinical manifestations and the laboratory findings are indistinguishable from those of the usual forms of parathyroid adenomas. Unlike parathyroid adenomas, parathyroid lipoadenomas can be functional or nonfunctional. We present a case of a function...

Primary hyperparathyroidism (PHPT) is a frequent endocrine disorder characterized by an excessive autonomous production and release of parathyroid hormone (PTH) by the parathyroid glands. This endocrinopathy may result from the development of a benign lesion (adenoma or hyperplasia) or from a carcinoma. Most of the PHPT cases occur sporadically; however, approximately 10% of the patients presen...