INTRODUCTION The relationship between peripheral 5-HT3A receptor mRNA level and risperidone efficiency in paranoid schizophrenia patients is still unknown. METHODS A total 52 first-episode and drug-naive paranoid schizophrenia patients who were treated with risperidone and 53 matched healthy controls were enrolled. Patients were naturalistically followed up for 8 weeks. Positive and Negative ...

This study examined agreement between clinical diagnoses and research diagnoses of schizophrenia for a sample of African American patients recently admitted to a psychiatric hospital. It also examined the association of cultural mistrust with disagreement between clinical diagnoses and research diagnoses of the paranoid subtype of schizophrenia. Complete data was available for 118 (77%) of the ...

Shared psychotic disorder develops in an individual in the context of a close relationship with another one who has an established delusion that he/she also believes. It is classified within paranoid disorder. Herein, we present a case of two sisters with their mother. The elder sister was the origin of paranoid delusion. Her delusion was with a dentist who tries his best to prevent her for mar...

BACKGROUND This study was concerned with investigating the mental health literacy of lay people in regard to the personality disorders. METHOD 223 participants responded to a questionnaire entitled 'eccentric people' which contained vignettes of 10 personality disorders which they rated as well as labelled. RESULTS Lay people recognize people with personality disorders as being unhappy, uns...

BACKGROUND Assessment of comorbid personality disorders (PDs) in patients with substance use disorders (SUDs) is challenging due to symptom overlap, additional mental and physical disorders, and limitations of the assessment methods. Our in-depth study applied methods to overcome these difficulties. METHOD A complete catchment area sample of 61 consecutively admitted patients with SUDs, with ...

Strangers made reliable judgments about personality traits after viewing one 30-s excerpt from interviews with anonymous target persons. Ratings were generated for 229 military recruits participating in a study of personality disorders. Approximately 28% of the recruits met DSM-IV criteria for a definite or probable personality disorder (PD). Several untrained undergraduate students rated each ...

Cessation of normal skin cleansing seen in geriatric or self-neglected patients can cause accumulation of keratinous crusts on the skin. In the extreme end of this spectrum is a condition known as Diogenes syndrome (DS). These patients may have psychiatric disorders like paranoid disorders, mood affection, or temporofrontal dementia. Subjects are mainly the elderly but few cases in younger age ...

Naming psychiatric disorders began long go with Hippocrates in 460-377 (b.c.). Pinel and Esquirol in the eighteenth century also proposed new concepts to classify psychiatric illnesses based on observations and data systematization. Nineteenth century, Kraepelin modified the classification, based also on observation and organization of symptoms. This is where the term early dementia came from. ...

BACKGROUND Sensory distortions of body image commonly occur during migraine, seizures, nondominant cortical infarcts and hallucinogen abuse. METHODS We report the case of a 30-year-old woman with paranoid schizophrenia presenting with postpartum onset multimodal sensory distortions in the absence of any neurological disorders or substance use. RESULTS Her symptoms involved persistent facial...

Trusting people requires evaluating them to assess their trustworthiness. Evaluating a stranger's intentions is likely to be one method of assessing trustworthiness. The present study tested the hypothesis that judgments of trustworthiness are associated with mind reading skills, also called theory of mind (ToM). We tested a group of healthy participants and a group of patients with paranoid sc...