نتایج جستجو برای: parakeratosis
تعداد نتایج: 275 فیلتر نتایج به سال:
Fifty-five patients with oral submucosal fibrosis and an equal number of patients with no evidence of the disease were studied. All patients underwent upper gastrointestinal endoscopy and any abnormality was noted. Multiple oesophageal biopsies were obtained from the upper end of the oesophagus and from any endoscopically observed abnormality. The histological changes in the two groups were ass...
F ox-Fordyce disease (FFD) (also known as apocrine miliaria) is a rare dermatologic condition characterized by multiple skin-colored, equidistant, perifollicular papules distributed in areas rich in apocrine glands. These areas typically include the axillae, anogenital, and periareolar regions. This condition primarily affects young females between 15 and 35 years of age, and rarely presents be...
disorder characterized by hyperkeratosis, acanthosis, accentuated rete ridges, focal spongiosis, and parakeratosis. It is usually caused by increased sebaceous gland activity, and manifests itself through the apparition of ill-defined eryhematous patches accompanied by fine scaling in areas of high sebum secretion, including the scalp, face, eyebrows, nasal alar creases, melolabial folds, ears,...
E4 CUTIS WWW.CUTIS.COM To the Editor: A 34-year-old woman presented for evaluation of dry mouth and painless peeling of the oral mucosa of 2 months’ duration. She denied any other skin eruptions, dry eyes, vulvar or vaginal pain, or recent hair loss. A recent antinuclear antibodies test was negative. The patient’s medical history was otherwise unremarkable and her current medications included m...
Progress He was investigated thoroughly to exclude an underlying infective process. Repeated full blood counts were normal, C-reactive protein was not elevated and erythrocyte sedimentation rate was 27 mm/hr. Anti-nuclear antibody and human immunodefi ciency virus (HIV) serology was negative. Tumour markers such as carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP) and prostate-specifi c a...
Hereditary nasal parakeratosis (HNPK), an inherited monogenic autosomal recessive skin disorder, leads to crusts and fissures on the nasal planum of Labrador Retrievers. We performed a genome-wide association study (GWAS) using 13 HNPK cases and 23 controls. We obtained a single strong association signal on chromosome 2 (p(raw) = 4.4×10⁻¹⁴). The analysis of shared haplotypes among the 13 cases ...
An 89-year-old Japanese woman was referred to us for evaluation of multiple scaly erythematous plaques with erosions that had developed over her entire body. She had received enteral feeding because of eating disorders for 9 months. Although she had been treated with topical steroid ointment and oral administration of prednisolone and terbinafine before admission to our department, there was no...
A 65-year-old man had an 8-year history of erosive, pustular, and atrophic lesions on his alopecic scalp (Figure1). The lesions developed since 1992, after treatment of actinic keratoses by topical fluorouracil and local trauma. Histologic examination of a skin biopsy specimen revealed an ulcerated atrophic epidermis with parakeratosis; a chronic inflammatory dermal infiltrate composed of lymph...
Esophagitis dissecans superficialis and eosinophilic esophagitis are distinct esophageal pathologies with characteristic clinical and histologic findings. Esophagitis dissecans superficialis is a rare finding on endoscopy consisting of the peeling of large fragments of esophageal mucosa. Histology shows sloughing of the epithelium and parakeratosis. Eosinophilic esophagitis is an allergic disea...
Amphiregulin (AR) is a heparin-binding, heparin-inhibited member of the epidermal growth factor (EGF) family and an autocrine growth factor for human keratinocytes. Previous studies have shown that AR expression is increased in psoriatic epidermis. To test the hypothesis that aberrant AR expression is central to the development of psoriatic lesions, we constructed a transgene (K14-ARGE) encodin...
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