introduction: bombesin (bn), a 14-amino acid neuropeptide, shows high affinity for the human grp (gastrin releasing peptide) receptors, which are overexpressed by a variety of cancers, including prostate, breast, pancreas, gastrointestinal, and small cell lung cancer. aim was to prepare [6-hydrazinopyridine-3-carboxylic acid (hynic0), d-tyr6, d-trp8] - bn [6-14] nh2 that could be easily labeled...

From the scanty evidence furnished by case reports, it is apparent that carcinoma of the pancreas is relatively rare in other animals as compared to its occurrence in man. According to the review of the literature on carcinoma of the pancreas in man by Kiefer (l), in 174,803 autopsies 1420 primary carcinomas of the pancreas were found, about 0.8 per cent, and among 50,494 admissions to Johns Ho...

A 42-years-old woman had undergone operation for cholecochal cyst with gallbladder cancer 9 years ago. Pathology revealed a polypoid mass in the gallbladder with liver infiltration as poorly differentiated adenocarcinoma. Computed tomography, magnetic resonance cholangiopancreatography, and endoscopic ultrasound showed a newly developed suspected solid nodule in the peripheral portion of cystic...

Modern imaging of pancreatic cancer remains a daily challenge both for detection and staging. Helical CT scanning, MRI, and more recently endoscopic ultrasound (EUS) all contribute. Demonstration of local vascular anatomy for assessing resectability is increasingly performed by non-invasive methods such as CT and MR angiography avoiding the need for traditional catheter angiograms. While a vari...

The use of in vivo contrast-enhanced magnetic resonance (MR) imaging as a surrogate for photosensitizer (verteporfin) dosimetry in photodynamic therapy of pancreas cancer is demonstrated by correlating MR contrast uptake to ex vivo fluorescence images on excised tissue. An orthotopic pancreatic xenograft mouse model was used for the study. A strong correlation (r = 0.57) was found for bulk inte...

A 74-year-old man suffered from jejunal perforation and adhesion to sigmoid colon due to adenocarcinoma associated with intraductal papillary mucinous neoplasm (IPMN) arising in a jejunal heterotopic pancreas. The jejunal lesion showed direct extension to the sigmoid colon, which was mistaken as sigmoid colon cancer by surgeons. Malignant transformation is a rare complication of a heterotopic p...

A case of invasive ductal carcinoma of an ectopic pancreas in the stomach in a 74-year-old woman is presented. A 4.0 cm gastric submucosal tumor (SMT) was resected surgically. Histologically, the tumor showed cystic tissue consisting of an ectopic pancreas with foci of a moderately differentiated tubular adenocarcinoma. In this tumor, small pancreatic tissues, acini, Langerhans islets, and duct...

Pancreas is one of the most important human organs, which lies at the back of stomach and close to abdomen. This organ is responsible for the release of enzymes or fluids, which help in easy digestion of food leading to release of energy in human body [1]. In the absence of pancreas failing to do its regular set of actions, human beings may get affected from diseases like diabetes [2]. Besides ...

The pancreas is an unusual location for metastases from other primary cancers. Rarely, pancreatic metastases from kidney or colorectal cancers have been reported. However, a variety of other cancers may also spread to the pancreas. We report an exceptional case of pancreatic metastasis from prostate cancer. Differences in management between primary and secondary pancreatic tumors make recogniti...

BACKGROUND Mass-forming focal pancreatitis (FP) may mimic pancreatic cancer (PC) on magnetic resonance (MR) imaging, and the preoperative differential diagnosis is often difficult. Recently, the usefulness of diffusion-weighted imaging (DWI) in the diagnosis of pancreatic cancer has been reported in several studies. PURPOSE To investigate if apparent diffusion coefficient (ADC) measurements b...