Coptidis Rhizoma and its isolated alkaloids are reported to possess a variety of activities, including neuroprotective and antioxidant effects. Thus, the anti-Alzheimer and antioxidant effects of six protoberberine alkaloids (berberine, palmatine, jateorrhizine, epiberberine, coptisine, and groenlandicine) and one aporphine alkaloid (magnoflorine) from Coptidis Rhizoma were evaluated via beta-s...

The tuber of Corydalis yanhusuo is a famous traditional Chinese medicine and found to have potent pharmacological effects, such as antinociceptive, antitumor, antibacterial, anti-inflammatory, and anti-depressive activities. Although there are several methods to be developed for the analysis and detection of the bioactive ingredients' alkaloids, so far, only few prominent alkaloids could be qua...

Enantia chlorantha (Dokita Igbo, Awogba, Awopa), depending on the dialect of Yoruba speaking people South west and (Erumeru), Eastern Nigeria. It is widely distributed along coasts West Central Africa common in forest regions belongs to family Annonaceae trade name yellow wood. an ornamental tree which may grow up 30 m high, with dense foliage spreading crown. The plant extracts have been used ...

DOI: 10.4328/JCAM.5156 Received: 15.06.2017 Accepted: 02.07.2017 Printed: 01.12.2017 J Clin Anal Med 2017;8(suppl 4): 390-4 Corresponding Author: Çiğdem Coşkun Türer, Department of Periodontology, Bulent Ecevit University, Faculty of Dentistry, 67600 Kozlu, Zonguldak, Turkey. T.: +90 3722613651 F.: +90 3722613603 E-Mail: [email protected] Öz Amaç: Bu çalışmanın amacı deneysel periodontitis ...

Malaria remains a major public health problem due to the emergence and spread of Plasmodium falciparum strains resistant to chloroquine. There is an urgent need to investigate new and effective sources of antimalarial drugs. This research proposed a novel method of fern-mediated synthesis of silver nanoparticles (AgNP) using a cheap plant extract of Pteridium aquilinum, acting as a reducing and...

Traditional Chinese medicine (TCM) has an ancient history and unique system, including theory, methodology, prescription, formulation and medicines. There are differences between TCM and chemical drugs. For TCM, the multiple components in vivo are possibly to be detected; the number of components is relatively restricted; they could represent the therapeutic effect of the parent recipe; the con...

Coptidis rhizoma (Coptis) and its alkaloids exert various pharmacological functions in cells and tissues; however, the oral absorption of these alkaloids requires further elucidation. The present study aimed to examine the mechanism underlying the poor absorption of alkaloids, including berberine (BER), coptisine (COP), palmatine (PAL) and jatrorrhizine (JAT). An ultra‑performance liquid chroma...

Zuojin formula (ZJ) is a traditional Chinese medicine (TCM) prescription consisted of Coptidis Rhizoma (CR) and Euodiae Fructus (EF), and has been used to treat gastrointestinal (GI) disease for more than 700 years. Fan-Zuojin formula (FZJ) is a related TCM prescription also consisted of CR and EF with the opposite proportion. In recent years, ZJ was getting more attention for its antitumor pot...