androctonus crassicauda is the second most frequent causes of scorpion sting in south-west iran. its venom can cause sever pain, autonomic, central nervous system (cns), muscle function disturbances, and death. appropriate medi­cal and nursing cares can lead to complete recovery with no sequel .the majority of scorpion stings are oligosympto­matic, occurring mainly on the hands and feet (about ...

Scorpion stings are a public health problem in many countries including Morocco. Cutaneous manifestations are rare, mainly local or loco-regional, exceptionally generalized. We report a case of photosensitization mimicking hydroa vacciniforme after scorpion sting, not yet described in the literature.

Recent improvements in mRNA display have enabled the selection of peptides that incorporate non-natural amino acids, thus expanding chemical diversity macrocycles beyond what is accessible nature. Such libraries incorporated acids at expense natural by reassigning their codons. Here we report an alternative approach to expanded amino-acid preserves all 19 (no methionine) and adds 6 resulting hi...

As a DNA receptor in the cytoplasm, cyclic GMP-AMP synthase (cGAS) contributes to recognition of abnormal cytoplasm and stimulator interferon genes (STING) signaling pathway. cGAS could mediate expression interferon-related genes, inflammatory-related factors, downstream chemokines, thus initiating immune response. The STING protein is key effector It widely expressed across cell types such as ...

468 Urticarial Vasculitis After Bee-sting Therapy June-Hyuk Lee, Sung Woo Park, An-Soo Jang, DoJin Kim, and ChoonSik Park. Respiratory and allergy, Soonchunhyang University Bucheon Hospital, Bucheon, South Korea; Division of Respiratory and Allergy Medicine, Soonchunhyang University Hospital, College of Medicine, Bucheon, South Korea. Background: Bee-sting therapy is one of the oriental traditi...

Toll-like receptors (TLRs) are the primary sensors of the innate immune system that recognize pathogenic nucleic acids including double-stranded plasmid DNA (dsDNA). TLR signaling activates multiple pathways including IRF3 which is involved in transcriptional induction of inflammatory cytokines (i.e. interferons (IFNs)). Phospholipid scramblase 1, PLSCR1, is a highly inducible IFN-regulated gen...

Lion's mane jellyfish (Cyanea capillata) stings cause severe pain and can lead to dangerous systemic effects, including Irukandji-like syndrome. As is the case for most cnidarian stings, recommended medical protocols in response to such stings lack rigorous scientific support. In this study, we sought to evaluate potential first aid care protocols using previously described envenomation models ...

scorpionism is a known significant problem of medical and social importance in many tropical and subtropical regions including the middle east. in iran, highest prevalence of scorpion sting about 60% of all the stings has been reported from khuzestan province. among the 21,000 cases of reported scorpion stung patients, 12% were caused by h. lepturus, but contributed to 95% of all moralities in ...

scorpionism is a known significant problem of medical and social importance in many tropical and subtropical regions including the middle east. in iran, highest prevalence of scorpion sting about 60% of all the stings has been reported from khuzestan province. among the 21,000 cases of reported scorpion stung patients, 12% were caused by h. lepturus, but contributed to 95% of all moralities in ...

INTRODUCTION People in tropical and semi-tropical areas are in danger of scorpion sting, and this can be a serious problem for them. Mortality due to scorpion sting in the tropical and semi-tropical areas of Iran is about 75%, and this makes scorpion sting in these areas a serious medical problem. Because of this problem, our aim was to assess the epidemiological aspects of scorpion sting in Ba...