نتایج جستجو برای: painful diabetic neuropathy

تعداد نتایج: 168554  

2015
Shinji Kamei Hideaki Kaneto Akihito Tanabe Shintaro Irie Yurie Hirata Masashi Shimoda Kenji Kohara Tomoatsu Mune Kohei Kaku

Diabetic neuropathy is the most common diabetic complication. Duloxetine, a serotonin noradrenaline reuptake inhibitor (SNRI), is widely used for the treatment of diabetic painful neuropathy (DPN) because of the efficacy and safety profile. Syndrome of inappropriate antidiuretic hormone secretion, which is strongly associated duloxetine, is a rare but occasionally life-threatening adverse effec...

Journal: :The Journal of pharmacology and experimental therapeutics 2011
Shao-Rui Chen Hong Chen Wei-Xiu Yuan Hui-Lin Pan

Diabetic neuropathy is a common cause of chronic pain that is not adequately relieved by conventional analgesics. The α(2)-adrenoceptors are involved in the regulation of glutamatergic input and nociceptive transmission in the spinal dorsal horn, but their functional changes in diabetic neuropathy are not clear. The purpose of the present study was to determine the plasticity of presynaptic and...

Journal: :iranian journal of public health 0
o tabatabaei-malazy mr mohajeri-tehrani sp madani r heshmat b larijani

background: diabetic peripheral neuropathy (dpn) accounts for 80% of diabetic foot ulceration; therefore neurologic examination plays a critical role in screening at risk patients. our objective was assessment the prevalence of dpn and related factors based on clinical findings. methods: this cross-sectional study was conducted on 124 diabetics who were randomly recruited from diabetes clinic o...

Journal: :acta medica iranica 0
laily najafi endocrine research center, institute of endocrinology and metabolism, iran university of medical sciences, tehran, iran. mohammad e khamseh endocrine research center, institute of endocrinology and metabolism, iran university of medical sciences, tehran, iran. mojtaba malek endocrine research center, institute of endocrinology and metabolism, iran university of medical sciences, tehran, iran. hamid r baradaran endocrine research center, institute of endocrinology and metabolism, iran university of medical sciences, tehran, iran. seyed mojtaba aghili department of emergency medicine, imam khomeini hospital, tehran university of medical sciences, tehran, iran. maryam kia department of internal medicine, ziaeian hospital, tehran university of medical sciences, tehran, iran.

clinical assessment of distal symmetric polyneuropathy (dpn) involves the evaluation of symptoms and signs. although there are numerous tools to evaluate dpn, there is still a need to determine the most sensitive, specific, and accurate tests to detect dpn in a busy outpatient clinical setting. a total of 107 patients with type 2 diabetes were examined using michigan neuropathy screening instru...

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