padre peptide

sheida shariat department of pharmaceutics, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran ali badiee nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran seyed amir jalali department of immunology, medical school, shahid beheshti university of medical sciences, tehran, iran mercedeh mansourian nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran seyed alireza mortazavi department of pharmaceutics, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran mahmoud reza jaafari biotechnology research center, nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s):tumor-associated antigen (taa) subunit-based vaccines constitute promising tools for anticancer immunotherapy. however, a major limitation in the development of such vaccines is the poor immunogenicity of peptides when used alone.the aim of this study was to develop an efficient vaccine delivery system and adjuvant to enhance anti-tumor activity of a synthetic her2/neu derived pept...

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Optimization of a Method to Prepare Liposomes Containing HER2/Neu-Derived Peptide as a Vaccine Delivery System for Breast Cancer

Journal: The Iranian Journal of Pharmaceutical Research 2014

Ali Badiee, Mahmoud Reza Jaafari, Seyed Alireza Mortazavi, Sheyda Shariat,

The purpose of this study was to optimize a method for the encapsulation of P5 peptide, a new designed peptide containing MHC class I epitopes from rat HER2/neu protein, into liposomes as an approach for breast cancer vaccine formulation. The efficiency of liposomal encapsulation of peptides is generally low and development of an optimized method to increase encapsulation efficiency is a big ch...

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new peptide based freeze-dried kit [99mtc-hynic]-ubi 29-41 as a human specific infection imaging agent

Journal: :iranian journal of nuclear medicine 2008

mostafa gandomkar reza najafi mohammad mazidi mostafa goudarzi seyed hassan mirfallah

introduction: ubiquicidin 29-41 (ubi) is a fragment of the cationic antimicrobial peptide that is present in various species including humans. the purpose of this study was to investigate radiochemical and biological characteristics of [6-hydrazinopyridine-3-carboxylic acid (hynic)]-ubi 29-41 designed for the labeling with 99mtc using tricine as coligand. methods: synthesis was preformed on a ...

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