BACKGROUND Radiolabeled analogs of the E. coli heat-stable enterotoxin (ST(h)) are currently under study as imaging and therapeutic agents for colorectal cancer. The aim of these studies is to compare in vitro and in vivo characteristics of two novel ST(h) analogs with appended DOTA chelating moieties. MATERIALS AND METHODS ST(h) analogs were synthesized with pendant N-terminal DOTA moieties ...

Let Pn be the class of polynomials of degree at most n and Bn be a class of operators that map Pn into itself. For every P ∈ Pn and B ∈ Bn, we investigate on |z| = 1, the dependence of ||B[P (R ·)]− B[P (r ·)]||q on ||P ||q, for every R > r ≥ 1 and q ≥ 1.

Marburger, D., Conley, S., Esker, P., MacGuidwin, A., Smith, D. 2013. Relationship between Fusarium virguliforme and Heterodera glycines in commercial soybean fields in Wisconsin. Plant Health Progress doi:10.1094/PHP-RS-13-0107. Fusarium virguliforme (syn. Fusarium solani f. sp. glycines), the causal agent of sudden death syndrome, and Heterodera glycines, soybean cyst nematode (SCN), are econ...

For complex valued sequences {ωn}∞n=1 of the form ωn = an + ibn with an ∈ R and bn ≥ 0, we prove inequalities of the form ∫ T 0 | ∑∞ n=p xne itωn |2dt 3 ∞n=p |xn|/(1+bn), for all sequences {xn} with ∑∞ n=1 |xn|/(1 + bn) < ∞. We apply these to prove exact null-controllability for a class of hinged beam equations with mild internal damping with either boundary control or internal control.

Tribological performance of polyalphaolefin 32, PAO, is investigated by adding two nanomaterials (graphene nanoplatelets, GnP, and hexagonal boron nitride nanoparticles, h-BN) an ionic liquid ([P 6,6,6,14 ][DEHP], IL1, [P 2,4,4,4 ][DEP], IL2, or ][(iC8) 2 PO ], IL3). Designed double hybrid nanodispersions are PAO/1 wt% ILX/0.05 GnP/0.1 h-BN (X = 1, 3). The best anti-friction behavior correspond...

Background Recently, 44Sc (T1/2 = 3.97 h, Eβ+av = 632 keV, I = 94.3 %) has emerged as an attractive radiometal candidate for PET imaging using DOTA-functionalized biomolecules. The aim of this study was to investigate the potential of using NODAGA for the coordination of 44Sc. Two pairs of DOTA/NODAGA-derivatized peptides were investigated in vitro and in vivo and the results obtained with 44Sc...

Biocompatible poly-[N-(2-hydroxyethyl)-d,l-aspartamide]-methoxypoly(ethyleneglycol)-hexadecylamine (PHEA-mPEG-C(16)) conjugated with 1,4,7,10-tetraazacyclododecan-1,4,7,10-tetraacetic acid-gadolinium (DOTA-Gd) via ethylenediamine (ED) was synthesized as a magnetic resonance imaging (MRI) contrast agent. Amphiphilic PHEA-mPEG-C(16)-ED-DOTA-Gd forms micelle in aqueous solution. All the synthesize...

severe congenital neutropenia (scn) is a rare primary immunodeficiency. different genes are found to be associated with scn, including ela2, hax1, was, gfi1, g-csfr. also, recently g6pc3 as a rare gene in scn has been reported. patients with g6pc3 often have cardiac and/or urogenital malformations. two patients with   persistent   severe   neutropenia,   recurrent   infections   and   maturatio...

Mg(SCN)2·4H2O can be converted into Mg(SCN)2·(4 − x)H2O·xTHF compounds with x = 2 and 4 by multiple recrystallization in THF. Heating of Mg(SCN)2·4THF leads to anisotropic lattice expansion, growing THF-disorder eventually Mg(SCN)2·2THF.

Light stimulates neuronal activity with subsequent expression of the protein product of the immediate early gene, c-fos, in the Suprachiasmatic Nuclei (SCN). Non-photic stimuli is also thought to modulate activity within the SCN. Here, we sought to determine the effects intrinsic stimuli, specifically, the states of sleep upon c-fos protein expression in the SCN. In 16 rats, c-fos protein expre...