OBJECTIVE Pinus eldarica (P. eldarica) is one of the most common pines in Iran which has various bioactive constituents and different uses in traditional medicine. Since there is no documented evidence for P. eldarica safety, the acute and sub-acute oral toxicities of hydroalcoholic extract of P. eldarica bark were investigated in male and female Wistar rats in this study. MATERIALS AND METHO...

The aim of this study was to investigate the effects of aqueous extract from Sarcodon aspratus on tenderization of the bovine longissimus dorsi muscles in comparison with commercial proteolytic enzymes. Furthermore, meat quality and muscle protein degradation were examined. We marinated meat with 2% Sarcodon aspratus extract, 2% kiwi extract, and 0.2% papain. Beef chunks (3×3×3 cm(3)) were mari...

This study investigated the effect of red ginseng extract on metastasis of colon cancer cells in vitro and in vivo. Wound healing migration, cell motility, invasion, and activity, protein expression, and mRNA expression of matrix metalloproteinases (MMPs) were examined in SW480 human colon cancer cells. SW480 cells were cultured with or without 100 μg/L PMA in the absence or presence of various...

conclusions: using n-butanolic c. coum extract in combination with ciprofloxacin offers a novel strategy to control biofilm-based infections caused by p. aeruginosa. results: the ability of biofilm formation by p. aeruginosa strains was quantitatively confirmed. the pcr method confirmed the existence of cup a gene (172 bp) in all studied strains. saponin content of the n-butanolic c. coum extra...

It was observed previously that New Zealand blackcurrant (NZBC) extract reduced slowing of the maximal 15 m sprint speed during the Loughborough Intermittent Shuttle Test. We examined the effect of NZBC extract on the performance of the Running Based Anaerobic Sprint Test (RAST, 6 × 35-m sprints with 10 seconds passive recovery) in trained youth and recreationally active football players. Fifte...

Article history: Received on: 14/01/2014 Revised on: 30/01/2014 Accepted on: 06/03/2014 Available online: 30/03/2014 Microbial colonization as biofilm is one of the reasons for the emergence of drug resistant strains. In the oral cavity, drug resistant strains limit the efficacy of oral hygiene practices. Enterococcus faecalis and Staphylococcus aureus have been reported as drug resistant bacte...

Insulin resistance plays a central role in the pathogenesis of type 2 diabetes mellitus. Ameliorating insulin resistance helps to improve glycaemic control and hence reduce the risk of development and progression of diabetic complications. The extract of Moringa oleifera has been shown to improve hyperglycaemia, however, little is known on its effect on insulin resistance and beta-cell function...

OBJECTIVE Opuntia humifusa (O. humifusa) Raf. has been used for the prevention and treatment of rheumatoid arthritis, inflammation, and cancer. Our study was designed to unveil the anti-nociceptive and anti-inflammatory effects of the methanolic extract of O. humifusa Raf stem (OHS). MATERIALS AND METHODS The anti-nociceptive effect was measured by hot plate, acetic acid-induced writhing, and...

Ethanol extract of Pleurotus eryngii (DC.) QUÉL has estrogen-like activities that protect against bone loss caused by estrogen deficiency. In the present study, we investigated the effect of P. eryngii on depression-like behavior and memory impairment in ovariectomized (OVX) rats. Immobility time during a forced swimming test was significantly longer for OVX rats than for sham-operated rats. Th...