INTRODUCTION Patients on long-term hemodialysis are at a higher risk of cardiovascular disease and premature mortality. It is generally believed that omega-3 supplementation can prevent cardiovascular events due to its anti-inflammatory and anti-atherosclerotic effects. MATERIALS AND METHODS Fifty-two hemodialysis patients were divided into 2 groups to receive omega-3 and placebo for 6 six mo...

Medication prescribing practice changed following the publications of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) in 2002 and the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC 7) in 2003. Few data are available on changes in hypertension control rates for patients initiat...

Chronic two-kidney, one clip (2K1C) renovascular hypertension is characterized by a largely angiotensin-independent elevated blood pressure (BP). We hypothesized that the long-term effect of hypertension would compromise endothelium-derived nitric oxide (NO) and diminish its influence in controlling renal perfusion. We determined the influence of endothelium-derived NO on renal hemodynamics and...

INTRODUCTION Diabetic Nephropathy (DN) is one of the main complications of diabetes mellitus, mostly ending to end-stage renal disease. Leptin and C-reactive protein (CRP), as inflammatory markers implicated in the progression of DN, increase in diabetes mellitus, while transferrin and albumin, as members of anti-oxidant defense mechanism, are found to decline. MATERIALS AND METHODS In a cont...

neuroinflammation is a disorder that causes neurological disease. neuroinflammation has a significant role in induce of multiple sclerosis (ms) and one of the situations that must be treated stops the ongoing process of inflammation against the cns by self-reactive lymphocytes. according to the successful results that were obtained from the pre-clinical phase of cell therapy, many studies were ...

s Cardiology 11 OC-005 Hypertrophic Cardiomyopathy in Iceland: MYBPC3 Founder Mutation Adalsteinsdottir B.*1, Teekakirkul P.2, Maron B.J.3, Gudbjartsson D.F.4, Holm H.4, Danielsen R.1, Seidman J.G.2, Seidman C.S.2, Gunnarsson G.T.5 1The National University Hospital of Iceland, Iceland; 2Harvard Medical School, United States; 3Minneapolis Heart Institute Foundation, United States; 4Decode Geneti...

background: functional appliances such as bionator have been used to treat class ii malocclusion. the purpose of this study was to compare the skeletal, dental and soft tissue effects of bionator appliances with multi-p (a newly developed appliance) in the treatment of class ii malocclusion. subjects and methods: 45 class ii children were chosen and randomly assigned to either the bionator or m...

PURPOSE To test whether employer matching of employees' monetary contributions increases employees' (1) participation in deposit contracts to promote weight loss and (2) weight loss. DESIGN A 36-week randomized trial. SETTING Large employer in the northeast United States. PARTICIPANTS One hundred thirty-two obese employees. INTERVENTIONS Over 24 weeks, participants were asked to lose 24...

CONTEXT AND OBJECTIVE Titrating the dosage of growth hormone (GH) to serum levels of insulin-like growth factor-I (IGF-I) is a feasible treatment strategy in children with GH deficiency (GHD) and idiopathic short stature (ISS). The objective was to assess the dose-sparing effect and theoretical safety of IGF-I-based GH therapy. DESIGN, SETTING AND PATIENTS This was a post hoc analysis of a pr...