Substantial injury can occur during reoxygenation of previously ischemic tissue in many experimental models, as the result of the generation of oxygen-derived free radicals. To test the antiradical activity of potentially protective compounds in this setting, we developed a simple screening system, applicable to fresh biopsy specimens, in which warm ischemia and reoxygenation of excised tissue ...

Peroxy-containing metabolitesare an interesting group amongbiological active natural compounds. These metabolites contain a peroxide group (-O-O-) in which each oxygen atom is bonded to the other oxygen an to another atom. β-Oxygen in hydroperoxide group is considered as moreactive.Present review describes research on more than 100 natural hydroperoxidesand rare acyclic peroxides isolated from ...

Induction of gap junctional communication (GJC) and antioxidant activities of carotenoids have been considered as biochemical mechanisms underlying the cancer-preventive properties of these compounds. beta-Carotene and other carotenoids, including those lacking provitamin A activity, proved to be active in both these parameters. The beta-carotene analogs retrodehydro-beta-carotene, echinenone, ...

Glycyrrhiza uralensis (or licorice) is a widely used Oriental herbal medicine from which the phenylflavonoids dehydroglyasperin C (DGC), dehydroglyasperin D (DGD), and isoangustone A (IsoA) are derived. The purpose of the present study was to evaluate the antioxidant properties of DGC, DGD, and IsoA. The three compounds showed strong ferric reducing activities and effectively scavenged DPPH, AB...

Reactive oxygen species are oxygen-based molecules readily reacting with various compounds. It is already known that they play significant role in many physiological as well as pathological body processes. The aim of our review is to briefly summarize our knowledge of possible ROS sources in the lung tissue.

The compounds Ln3Cu4P4O2ÿx (Ln = Pr, Sm) were prepared by annealing the elemental components in a NaCl/KCl flux. They crystallize with an ordered Zr3Cu4Si6-type structure (space group I4/mmm, Z = 2), which was refined from single-crystal X-ray data for both compounds; Pr3Cu4P4O2ÿx: a = 397.8(1), c = 2658.7(3) pm, R = 0.046 for 235 structure factors and 19 variable parameters; Sm3Cu4P4O2ÿx: a = ...

Deoxygenation of various types of N-oxides including both heterocyclic and alkyl(aryl)amine derivatives has successfully been developed by the copper-catalyzed oxygen atom transfer using diazo compounds as the oxygen acceptor. The reaction proceeds smoothly over a broad range of substrates with excellent functional group tolerance under mild conditions.

Introduction: Triple oxygen isotope measurement was once an exclusive practice in meteorite research [1]. Since 1980s, many compounds on Earth have been found to possess triple oxygen isotope compositions that deviate from terrestrial fractionation line [2, 3]. Some of them form minerals and rocks, which can be preserved in geological records and serve as a solid archive for past Earth system h...

Nine phenolic compounds were metabolized by the soft rot fungus Lecythophora hoffmannii via protocatechuic acid and subsequently cleaved by protocatechuate 3,4-dioxygenase as determined by oxygen uptake, substrate depletion, and ring cleavage analysis. Catechol was metabolized by catechol 1,2-dioxygenase. Fungal utilization of these aromatic compounds may be important in the metabolism of wood ...