background: the interaction between follicular cells and oocyte leads to a change in gene expression involved in oocyte maturation processes. objective: the purpose of this study was to quantify the expression of more common genes involved in follicular growth and oocyte developmental competence. materials and methods: in this experimental study, the expression of genes was evaluated with qrt-p...

background: breast cancer is the most common malignancy in women. breast cancer type 1 susceptibility gene (brca1) is a tumor suppressor gene, involved in dna damage repair and in 81% of the breast-ovarian cancer families were due to brca1. in some clinically investigated genes, the intragenic marker polymorphism is important and the screening of such mutations is faster by using short tandem r...

a 52-year-old post-menopausal female was admitted to the emergency room due to acute onset of abdominal pain in the right lower quadrant. there was no history of trauma of the abdomen. contrast-enhanced multi-detector computed tomography (mdct) of the abdomen and pelvis revealed a massive right retroperitoneal hematoma and contrast extravasation from a right ovarian artery aneurysm. digital sub...

polycystic ovarian syndrome is a hetrogenous condition with a broad clinical and pathologic spectrum that may reflect the effects of diverse etiologic factors. polycystic ovarian syndrome is an abnormality in the maturation of the follicles which can result in abnormal composition of follicular fluid. by analysis and comparison of the biochemical composition of human follicular fluid in normal ...

background: to investigate the frequency of different types of gynecological tumors among patients who were operated in shahid sadoughi hospital, yazd, iran, for 3 years. material and methods: this study investigated 101 patients with gynecological tumors from march 21.2008 to march 20 2011.. lesions were considered in 5 groups according to the prevalence of malignancy. lymph node and peritonea...

objective: the goal of this study is to evaluate the efficacy of intraperitoneal (jp) cisplatin as consolidation treatment, in epithelial ovarian cancer patients with pathologically negative surgical reassessment, following first-line platinum-based chemotherapy. methods: this study included 22 patients with figo stage (iic- iv) epithelial ovarian cancer (eoc) which had no evidence of disease a...

forty ewes (3-6 years of age, average weight 41.2 kg)were randomly chosen from the flock of the sheep experiment station of tripoli university. ewes were divided into two groups, control group (c) received untreated barley straw and treatment group (t) received barley straw treated with 10% urea solution applied as 40% (v/w). barley straw was sprayed with molasses when fed to animals. both grou...

Infertility is a main manifestation of endometriosis, though the exact pathogenesis endometriosis-associated infertility remains unclear. Compromised ovarian functions may be one causes endometriosis related infertility. The function can classified into three basic elements, (1) production hormones, (2) maintenance follicular development until ovulation, and (3) reservoir dormant oocytes (ovari...

AIMS To find specific magnetic resonance imaging (MRI) features to differentiate metastatic ovarian tumors from primary epithelial ovarian cancers. METHODS Eleven cases with metastatic ovarian tumors and 26 cases with primary malignant epithelial ovarian cancers were retrospectively studied. All features such as patient characteristics, MRI findings and biomarkers were evaluated. The differen...

BACKGROUND Ovarian tissue cryopreservation is a technique for fertility preservation addressed to prepubertal girls or to patients for whom no ovarian stimulation is possible before initiation of gonadotoxic treatments. Autotransplantation of frozen-thawed ovarian tissue is the only available option for reuse but presents some limitations: ischemic tissue damages post-transplant and reintroduct...