OBJECTIVE To review the malignant potential of endometriosis based on epidemiologic, histopathologic, and molecular data. DESIGN Literature review. RESULT(S) The pathogenesis of endometriosis remains unclear. The histopathologic development of endometriosis has undergone long-term investigation. Studies have confirmed histologic transition from benign endometriosis to ovarian malignancy, in...

Presence of ovarian tumors in pregnancy is uncommon. In most cases, they are benign, torsion the common complication. Management can be conservative or surgical depending on size, clinical presentation, gestational age, available resources etc. advances imaging techniques have made decision making easier. We present a case primigravida aged 24 years, with 18 weeks’ pain abdomen. She had large m...

BACKGROUND Torsion of the ovary is a rare but serious cause of gynecologic surgical emergency. Specific laboratory markers that support the preoperative diagnosis of ovarian torsion are not currently available in the clinical routine. The aim of this study was to investigate the diagnostic value of plasma D-dimer level as an early indicator of ovarian torsion in an experimental rat ovarian tors...

Currently, laparoscopic cystectomy is the first-line therapy for ovarian benign cysts that are resistant to current therapies. There are different studies that point to ovarian reserve damage due to laparoscopic cystectomy. In this study, we evaluate the ovarian damage following laparoscopic cystectomy for non-endometriosis cysts using ultrasound and pathology findings. This is a prospective co...

Background: Mucinous ovarian tumors differ from other types of epithelial cancers in their clinical behaviour and the need for innovative treatment approaches to achieve improved patient outcomes. Immunohistochemistry plays an important role diagnosis differentiates primary secondary mucinous tumors. To know distribution expression CK7 CK20 ovary gastrointestinal tract.Methods: Ninety eight cas...

We report a case of florid polypoid endometriosis presenting with advanced bulky disease in pelvis with serum CA-125 levels of 7844U/ml. The extent of tumor, CT scan findings, elevated serum CA-125 levels were suggestive of ovarian malignancy. Histopathology demonstrated endometrial glands and stroma. Glands were neither crowded nor complex and were separated by a fibromatous stroma that contai...

Primary esophageal liposarcoma is a rare malignancy, with only 25 cases reported in the English literature. In this report, we present a new case of giant esophageal liposarcoma in a 49-year-old woman with a family history of upper gastrointestinal tract cancer. This was a transmural tumor located in the lower esophagus. Subtotal esophagectomy was successfully performed, and histopathology reve...

BACKGROUND The incidence of ovarian cancer is thought to be increasing in developing countries and little is known about the pattern and incidence of this disease in South-East Nigeria. AIMS The objectives of the study were to determine the incidence, describe the pattern and management of ovarian cancer at a tertiary medical center in Enugu South East Nigeria. MATERIALS AND METHODS This wa...

Angiosarcomas are rare malignancies of endothelial origin.Peritoneal angiosarcomas are rare and behave aggressively, resulting in 100% mortality. Its incidence is approximately 0.01 per 100,000 cases.. A 55 year old female presented with complaints of vomiting for 2 days. USG abdomen showed? Mesothelioma with moderate ascites and bilateral pleural effusion. CT of abdomen and pelvis showed? Ovar...

Background and Objective: Xanthogranulomatous oophritis is an uncommon, non-neoplastic, chronic process in which the affected organ is destroyed by massive cellular infiltration of foamy histiocytes admixed with multinucleated giant cells, plasma cells, fibroblasts, neutrophils, and foci of necrosis. The etiology of this entity is unknown, but it shares histopathological findin...