Motivated by the low-collisionality of gas accreted onto black holes in Sgr A* and other nearby galactic nuclei, we study a family of 2D advective accretion solutions with thermal conduction. While we only impose global inflow, the accretion flow spontaneously develops bipolar outflows. The role of conduction is key in providing the extra degree of freedom (latitudinal energy transport) necessa...

Visual impairment due to glaucoma currently impacts 70 million people worldwide. While disease progression can be slowed or stopped with effective lowering of intraocular pressure, current medical treatments are often inadequate. Fortunately, three new classes of therapeutics that target the diseased conventional outflow tissue responsible for ocular hypertension are in the final stages of huma...

Alluvial aquifers in mountainous regions cover typically a limited area. Their contribution to catchment storage and outflow is rarely isolated; alluvial groundwater discharge under gauging stations is generally assumed negligible; and hydrological models tend to lump alluvial storage with other units. The role of alluvial aquifers remains therefore unclear: can they contribute significantly to...

We propose a general methodology to measure labour market dynamics, inspired by the search and matching framework, based on estimate of transition rates between states. show how instantaneous starting from discrete time observations provided in longitudinal datasets, allowing for any number illustrate potential such using Italian data. First, we decompose unemployment rate fluctuations into inf...

We propose a “two-stage” model for the effects of feedback from a bright quasar on the cold gas in a galaxy. It is difficult for winds or other forms of feedback from near the accretion disk to directly impact (let alone blow out of the galaxy) dense molecular clouds at ∼kpc. But if such feedback can drive a weak wind or outflow in the hot, diffuse ISM (a relatively “easy” task), then in the wa...

The effects of bimatoprost on aqueous humor dynamics were quantified in monkey eyes. Uveoscleral outflow was measured by the anterior chamber perfusion method, using FITC-dextran. Total outflow facility was determined by the two-level constant pressure method. Aqueous flow was measured with a scanning ocular fluorophotometer. Uveoscleral outflow was 0.96 +/- 0.19 muL min(-1) in vehicle-treated ...

AIMS This study investigated the clinical and physiological significance of the dynamic left ventricle outflow gradient observed in some patients during dobutamine stress echocardiography. METHODS Three hundred and ninety-four consecutive patients completed dobutamine stress echocardiography using Doppler echocardiography to assess the presence of myocardial ischaemia and left ventricular out...

THIS study deals with the problem of the regulation of the intra-ocular pressure and the influence of pressure on the formation and the resistance to outflow of the aqueous humour. The main experimental approach has been to analyse the relationship between the steady state intra-ocular pressure and varied rates of flow of fluid through the anterior chamber of living and dead eyes. In the experi...

PURPOSE To determine improvement in outflow facility (C) in human anterior segments implanted with a novel Schlemm's canal scaffold or two trabecular micro-bypasses. METHODS Human anterior segments were isolated from 12 pairs of eyes from donors with no history of ocular disease and then perfused at 50, 40, 30, 20, and 10 mm Hg pressures for 10 minutes each. Baseline C was calculated from per...

A survey of CO(3–2) emission from optically visible oxygen–rich Mira variable stars within 500 pc of the sun was conducted. A molecular envelope was detected surrounding 36 of the 66 stars examined. Some of these stars have lower outflow velocities than any Miras previously detected in CO. The average terminal velocity of the ejected material was 7.0 km s 1, about half the value found in Miras ...