We report a rare case of osteonecrosis of the jaw following necrotizing gingivitis in a Japanese AIDS patient. Intraoral examination showed exposed necrotic bone in the left mandible and spontaneous loss of teeth. This patient was successfully treated with highly active anti-retroviral therapy combined with minimally invasive surgical procedures to remove the osteonecrosis of the jaw.

Validation of claims-based algorithms to identify serious hypersensitivity reactions and osteonecrosis of the jaw has not been performed in large osteoporosis populations. The objective of this project is to estimate the positive predictive value of the claims-based algorithms in older women with osteoporosis enrolled in Medicare. Using the 2006-2008 Medicare 5% sample data, we identified poten...

BACKGROUND Osteonecrosis is common in systemic lupus erythematosus (SLE) and often disabling. The role of glucocorticoids in its development is well known. OBJECTIVE To explore other possible risk factors for osteonecrosis in SLE. METHODS A nested matched case-control study undertaken in the context of a large, longitudinal, multiethnic lupus cohort (LUMINA), currently formed of 571 SLE pat...

OBJECTIVES To report the rates of osteonecrosis and subtalar arthritis after talar neck fractures and to examine if rates have changed over time. DATA SOURCES A systematic review and meta-analysis of the English literature was performed using EMBASE, MEDLINE, CENTRAL, and Cochrane in November 2011 and updated in November 2014. STUDY SELECTION Inclusion criteria were studies examining talar ...

Background: Medication-Related Osteonecrosis of the Jaw (MRONJ) can occur as an adverse reaction to several antiresorptive medications such bisphosphonate. It presents clinically a necrotic exposed bone. Several factors including tooth extraction and ill-fitting dentures increase risk osteonecrosis development. Case Report: A 72-year-old female who had partial denture that caused bone traumatic...

Medication-related osteonecrosis of the jaw (MRONJ) is an adverse drug reaction that occurs in a very different ways and affects patients with complex medical histories. The objective this study to evaluate prognosis surgically treated drug-related osteonecrotic lesions verify whether platelet concentrates used during surgical procedure can improve prognosis.The was performed by analyzing sampl...

BACKGROUND Pulsed electromagnetic fields (PEMF) stimulation has been used successfully to treat nonunion fractures and femoral head osteonecrosis, but relatively little is known about its effects on preventing steroid-induced osteonecrosis. The purpose of the study was to investigate the effects of PEMF stimulation on the prevention of steroid-induced osteonecrosis in rats and explore the under...

BACKGROUND Steroid associated osteonecrosis is difficult to treat. Teriparatide, as the only one bone anabolic drug, has achieved very promising effect in osteoporosis and other bone skeletal diseases. We carried out this animal study to evaluate the effect of subcutaneous injection of teriparatide for the steroid induced femoral head necrosis in a rat model. METHODS 24 Sprague-Dawley male ad...