Obstructive sleep apnea syndrome (OSAS) is char­ acterized by repeated partial or complete collapse of the pharynx during sleep, which results in apnea or hypopnea, associated with oxygen desaturation and arousal from sleep. OSAS is associated with meta­ bolic syndrome, cardiovascular diseases, and neu­ ropsychological sequelae. In addition, traffic and work-related accidents are frequently att...

We observed the curative effect of the 3C insulin system in combination with non-invasive ventilation in a patient with type 2 diabetes and obstructive sleep apnea syndrome (OSAS). The 3C insulin pump is a system of devices that closely monitors and effectively regulates blood glucose levels. Non-invasive ventilation has been shown to be an effective treatment for OSAS. A type 2 diabetes patien...

WINNING ABSTRACT: Circulating levels of TNF-a are elevated in Obstructive Sleep Apnoea Syndrome (OSAS) and likely contribute to associated cardiovascular diseases. Furthermore, TNF-a has been suggested as a mediator of excessive daytime sleepiness (EDS). We investigated the predictors of TNF-a in OSAS in large, well-selected patient and control cohorts. We undertook a prospective study of 30 no...

OBJECTIVE To determine the role of genetic mechanisms in the development of pediatric obstructive sleep apnea syndrome (OSAS). DESIGN Genetic-epidemiologic survey of families of index children with laboratory-confirmed OSAS. SETTING Tertiary care academic medical center. PARTICIPANTS Six-hundred nap polysomnograms performed in our institution's pediatric sleep laboratory over a 6-year per...

Objective. Objective. Previous studies showed that obstructive sleep apnea syndrome (OSAS) was associated with liver diseases such as elevated liver enzyme levels and hepatic steatosis. The aim of this study was to assess the relationship between serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels and OSAS and its severity. Methods. A total of 617 patients who under...

INTRODUCTION Obstructive sleep apnea syndrome (OSAS) is a frequent breathing disorder occurring during sleep that is characterized by recurrent hypoxic episodes and sleep fragmentation. It remains unclear whether OSAS leads to structural brain changes, and if so, in which brain regions. Brain region-specific gray and white matter volume (GMV and WMV) changes can be measured with voxel-based mor...

Background: Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder characterized by recurrent upper airway collapse during sleep. Recently, some hematological parameters as red cell distribution width (RDW), mean platelet volume (MPV), and platelet distribution width (PDW) have been emerged as inflammatory biomarkers. Limited, controversial data is available on the association betwe...

BACKGROUND The purpose of this study was to determine the role of obstructive sleep apnea syndrome (OSAS) as an independent risk factor for the development of left ventricular diastolic abnormalities. Moreover, we tested the hypothesis that nasal continuous positive airway pressure (nCPAP) improves such alterations in OSAS patients by eliminating apneic events. METHODS AND RESULTS In this pro...

The obstructive sleep apnea syndrome (OSAS) occurs in patients of all ages, from the premature infant to the elderly. Much remains unknown about the pathophysiology of the syndrome. However, research suggests that OSAS in all age groups is due to a combination of both anatomic airway narrowing and abnormal upper airway neuromotor tone. The anatomic predisposing factors for OSAS differ over the ...

STUDY OBJECTIVES Obstructive sleep apnea syndrome (OSAS) is associated with impairment of cognitive function, and improvement is often noted with treatment. Golf is a sport that requires a range of cognitive skills. We evaluated the impact of nasal positive airway pressure (PAP) therapy on the handicap index (HI) of golfers with OSAS. METHODS Golfers underwent a nocturnal polysomnogram (NPSG)...