Alk(en)yl trisulfides (R-SSS-R') are organosulfur compounds produced by crushed garlic and other Allium vegetables. We found that these compounds exhibit potent anticancer effects through the reaction with microtubules, causing cell cycle arrest. Nine alk(en)yl trisulfides including dimethyl trisulfide, diethyl trisulfide, dipropyl trisulfide (DPTS), dibutyl trisulfide, dipentyl trisulfide, dia...

Lithium–sulfur batteries (LSBs) with high theoretical capacity are regarded as the most promising candidates for next-generation energy storage systems. However, low conductivity, volume change, and shuttle effect need to be addressed before commercialization of LSBs. Organosulfur covalent C?S bonds can solve these problems when applied different components Recent advances application organosul...

Bioactive compounds possess different health benefits. Onion contains various bioactive compounds, such as organosulfur flavonols, ascorbic acids, and carbohydrate prebiotics, its by-products have more content of flavonoids than the bulb. Diallyl monosulfide, diallyl disulfide, trisulfide, tetrasulfide are major whereas quercetin, kaempferol, anthocyanin, luteolin considered main flavonoids. As...

Garlic has been used throughout the world to treat coughs, toothache, earache, dandruff, hypertension, hysteria, diarrhoea, dysentery, diptheria, vaginitis and many other conditions. Garlic contains a complex mixture of oil and water-soluble organosulfur compounds. Diallyl disulfide (DADS), an oil-soluble constituent of garlic seems to be effective in reducing tumour cells originating from colo...

The title compound classes, (carbamoyl)sulfenyl chlorides and ((carbamoyl)dithio)carbonyl chlorides, have been implicated previously as unstable, albeit trappable, intermediates in organosulfur chemistry. The present work reports for each of these functional groups: (i) several routes to prepare it in the N-methylaniline family; (ii) its direct structural characterization by several spectroscop...

N-acetylcysteine (NAC) and S-methylcysteine (SMC), water soluble organosulfur compounds contained in garlic, were evaluated for chemoprevention of hepatocarcinogenesis after 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) initiation in rats. Intergastric treatment with NAC or SMC five times a week resulted in decreased numbers and areas of preneoplastic, glutathione S-transferase placenta...

Pyridinethiones are important ligand precursors of coordination complexes of therapeutic value. In aqueous solution, pyridinethiones can dimerize and tautomerize to the corresponding thiols. However, the tautomerism of pyridinethiones, which can impact on therapeutic performance, is yet not fully understood. To resolve this important issue, we have carried out ab initio and DFT calculations to ...

The removal of sulfur by deep hydrodesulfurization is expensive and environmentally unfriendly. Additionally, not separated completely from heterocyclic poly-aromatic compounds. In nature, several microorganisms (Rhodococcus erythropolis IGTS8, Gordonia sp., Bacillus Mycobacterium Paenibacillus sp. A11-2 etc.) have been reported to remove petroleum fractions. All these microbes recalcitrant org...