BACKGROUND Sedation and/or analgesia can relieve the patient-ventilator asynchrony. However, whether sedation and/or analgesia can benefit the clinical outcome of the patients with interface intolerance is still unclear. METHODS A retrospective study was performed on patients with interface intolerance who received noninvasive positive pressure ventilation (NIPPV) after extubation in seven in...

imaging of the kidneys and urinary tract has a significant and critical role for diagnosis of genitourinary system diseases. although technological progress goes toward less invasive approaches, some of the current methods are still invasive and annoying. voiding cystourethrography (vcug) is the best and most accurate method for diagnosis and grading of vesicoureteral refl ux. vcug is a distres...

Anxiolysis and sedation with oral midazolam are common practice in paediatric anaesthesia. However, good or excellent results are seen in only 50-80% of cases. For this reason, we investigated if addition of a low dose of oral ketamine (MIKE: ketamine 3 mg kg-1, midazolam 0.5 mg kg-1) resulted in better premedication compared with oral midazolam 0.5 mg kg-1 or ketamine 6 mg kg-1 alone, in a pro...

Objective: To assess the efficacy and safety of use midazolam as monotherapy, compared to associated hydroxyzine for minimum moderate sedation children in dental offices, using data obtained from clinical trials. Material Methods: A systematic review protocol was developed registered on PROSPERO (CR42020208633). An electronic search carried out Pubmed, Lilacs, Science Direct, Open Gray, Web Sci...

BACKGROUND Anesthesia care has been provided by diverse health professionals worldwide, but little is known about anesthesiologists' views about this. Using a survey, we sought the opinions of a group of Brazilian anesthesiologists regarding nitrous oxide/oxygen and oral minimal/moderate sedation performed by dentists. METHODS A 3-part postal questionnaire was sent to 206 physician anesthesio...

Moderate and deep sedation can be provided using several routes of drug administration including oral (PO), inhalation, and parental injection. The safety and efficacy of these various techniques is largely dependent on pharmacokinetic principles. This continuing education article will highlight essential principles of absorption, distribution, and elimination of commonly used sedative agents.

This article describes two collaborative paired student-preceptor efforts. One project resulted in the implementation of a hospital-wide oral care protocol, and the second enhanced the admission assessment process for adult patients at risk for respiratory compromise after sedation and/or receipt of narcotic analgesia. Recommendations for staff development are addressed.

OBJECTIVE To compare the effectiveness of oral midazolam and chloral hydrate on anxiety and sedation at various stages of pre-operative period in congenital heart surgery patients. STUDY DESIGN Cross-sectional comparative study. PLACE AND DURATION OF STUDY Operating rooms of The Aga Khan University Hospital, Karachi, from October 2009 to December 2010. METHODOLOGY Sixty-six patients betwe...

BackgroundAlthough midazolam and ketamine are widely administrated as oral premedications for children, only a few studies have investigated the cardiovascular, respiratory and sedative effects of these drugs in children with congenital heart disease (CHD). MethodsWe compared three methods of administering midazolam and ketamine and a combination of these two drugs as an oral premedication in 1...