Introduction: The quality of life is defined as the individual's sense of well-being and their satisfaction with daily work as influenced by dental and oral conditions. Oral diseases are very common and have impacts on the different aspects of individual's life and can change their social performances roles, in other words, they can change the quality of life. The aim of this study was to evalu...

BACKGROUND Pain in the head neck area is an early symptom in oral cancer, supporting the hypothesis that cancer cells control the activities of surrounding nociceptors at the site of the tumor. Several reports implicate TRPV1 and TRPA1 in cancer pain, although there is a large gap in knowledge since the mechanisms for tumor-induced activation of these TRP receptors are unknown. Interestingly, T...

Background: Surgical extraction of impacted mandibular third molar is one of the commonest oral surgical procedures. It is frequently associated with sequelae such as postoperative pain, swelling and trismus, which is known to have an impact on the quality of life of the patients. The aim of this study was to determine the effect of a single dose of pre-operative oral dexamethasone on postopera...

The analgesic effect of ketamine is primarily based on the antagonism of the N-methyl-d-aspartate (NMDA) receptor. Activation of NMDA receptors may play a crucial role in the pathogenesis of chronic pain. Little formal research has been performed on the efficacy and safety of ketamine in chronic pain, especially concerning long-term oral administration. This review provides an overview of the a...

Opioids continue to be first-line pharmacotherapy for patients suffering from cancer pain. Unfortunately, subtherapeutic dosage prescribing of pain medications remains common, and many cancer patients continue to suffer and experience diminished quality of life. A large variety of therapeutic options are available for cancer pain patients. Analgesic pharmacotherapy is based on the patient's sel...

oral health problems, among the most prevalent comorbidities related to addiction, require more attention by both clinicians and policy-makers. our aims were to review oral complications associated with drugs, oral health care in addiction rehabilitation, health services available, and barriers against oral health promotion among addicts. drug abuse is associated with serious oral health proble...