نتایج جستجو برای: oral drug administrations

تعداد نتایج: 813791  

Journal: :British journal of clinical pharmacology 2008
Bo-Hyung Kim Hyeong-Seok Lim Jae-Yong Chung Jung-Ryul Kim Kyoung Soo Lim Dong-Ryul Sohn Joo-Youn Cho Kyung-Sang Yu Sang-Goo Shin Jae-Seung Paick In-Jin Jang

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT The phosphodiesterase (PDE) type 5 inhibitor is a widely used agent that facilitates penile erection. Udenafil is newly developed as a PDE-5 inhibitor. WHAT THIS STUDY ADDS This is the first study to determine the safety, tolerability and pharmacokinetics of udenafil in healthy subjects. Udenafil was safe and well tolerated in healthy Korean subjects. ...

2008
M. Porritt A. Poling

In a study of working memory, the performance of rats under titrating-delayednonmatching-to-position (TDNMTP) procedures was examined. Overall accuracy and the number of trials completed were inversely related to titration value, whereas the highest delay attained was directly related to titration value. When given intraperitoneally, scopolamine significantly reduced the highest delay attained ...

Journal: :Biochimica et biophysica acta 2000
C Oja P Tardi M Schutze-Redelmeier P R Cullis

The generation of an immune response can dramatically alter the circulation lifetime of a targeted liposome, particularly when the response is generated against the surface-coupled ligand. Following repeated administrations, rapid elimination of the carrier system is observed, thereby limiting potential applications for targeted liposomes in a therapeutic setting. In this study, we have investi...

Journal: :iranian journal of pharmaceutical research 0
mohammad reza aghasadeghi department of hepatitis and aids, pasteur institute of iran, tehran, iran. seyed davar siadat department of hepatitis and aids, pasteur institute of iran, tehran, iran. mehdi shafiee ardestani department of hepatitis and aids, pasteur institute of iran, tehran, iran. department of radiopharmaceutical sciences, faculty of pharmacy, tehran university of medical sciences, tehran, iran. ali jabbari arabzadeh department of radiopharmaceutical sciences, faculty of pharmacy, tehran university of medical sciences, tehran, iran. mitra elmi department of radiopharmaceutical sciences, faculty of pharmacy, tehran university of medical sciences, tehran, iran. hadi fathi moghaddam department of physiology and physiology research center, jundishapur university of medical sciences, ahvaz, iran.

the aim of this research was to investigate the cyclooxygenase-2 (cox-2) selective inhibition effect on haloperidol-induced catatonia. in this study, the effect of orally, acutely and sub-chronically administrations of compound 11b [1-(phenyl)-5-(4-methylsulfonylphenyl)-2-ethylthioimidazole] (2, 4 and 8 mg/kg), a newly selective cox-2 inhibitor, was investigated against the haloperidol-induced ...

Journal: :The British journal of ophthalmology 2008
M N Wiggins R A Harper R D Landes P S O'Sullivan

BACKGROUND/AIM Oral examinations are required for board certification in Ophthalmology in the USA. The current literature offers no recommendation on the number of administrations during residency. The purpose of this study was to determine how often oral examinations (OEs) should be administered and what effects repeated OEs might have on residents' comfort level with OEs and confidence level ...

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