Fibronectin and laminin are clinically relevant plasmin receptors in the eye. Located at the vitreoretinal interface, they are cleaved by ocriplasmin (Microplasmin, ThromboGenics, Iselin, NJ), a novel ophthalmic medication. A series of clinical trials to study ocriplasmin for the treatment of vitreoretinal diseases such as vitreomacular traction, macular hole, and exudative age-related macular ...

Segmentation of anatomical and pathological structures in ophthalmic images is crucial for the diagnosis and study of ocular diseases. However, manual segmentation is often a time-consuming and subjective process. This paper presents an automatic approach for segmenting retinal layers in Spectral Domain Optical Coherence Tomography images using graph theory and dynamic programming. Results show...

Inflammation of the eye is often times seen in association with systemic inflammatory diseases. Understanding the various forms of ocular involvement in these conditions is important as untreated ophthalmic involvement can lead to severe vision loss. In addition to providing a basic framework for diagnosis and treatment, this review will highlight the ocular manifestations of the following syst...

Aim: To investigate the effects of a non-steroidal anti-inflammatory drug (NSAID) ophthalmic solution on latanoprost induced intraocular pressure (IOP) reduction using normal volunteers. Methods: This study was conducted as a prospective and observer masked clinical trial. 13 normal volunteers were enrolled. After measurement of basal IOP and ophthalmic examination, latanoprost ophthalmic solut...

operatively, we suspected that this most likely represented a benign smooth muscle tumor that had eroded through the iris root. Amyloid can occur as a localized ocular or widespread systemic process. Approximately 4% of amyloid deposits in the head and neck region involve the orbit. Amyloid deposits in ophthalmic structures can occur as a primary or secondary process. Primary deposits (which ca...

Genetics in general and more specifically ophthalmic genetics are areas that ophthalmologists tend not to focus too much on – during training and in practice. Undergraduate medical training and ophthalmology residency in India traditionally place more emphasis on diagnostic and surgical skills rather than other areas such as genetic analysis and genetic counseling. This is surprising considerin...

Aim: To investigate the effects of a non-steroidal anti-inflammatory drug (NSAID) ophthalmic solution on latanoprost induced intraocular pressure (IOP) reduction using normal volunteers. Methods: This study was conducted as a prospective and observer masked clinical trial. 13 normal volunteers were enrolled. After measurement of basal IOP and ophthalmic examination, latanoprost ophthalmic solut...

although ancient greek physicians studied a great number of ocular diseases in their medical texts such as glaucoma, cataract, trachoma, chalazion, trichiasis, entropion, ectropion and pterygion, in ancient greek art there were only few examples which represent ophthalmic diseases. these examples are found especially in portraits, and the ophthalmological disease is an important feature of the ...

The literature review discusses the impact of scheduled hemodialysis on state anterior part eye, chorioretinal complex, central and peripheral vision. procedure is accompanied by a decrease in basal tear production, quickening film break-up, an abnormal ocular surface disease index. Thinning corneal center not significant keratometric changes. Intradialytic thinning choroid reduction perfusion ...