BACKGROUND Conjunctivitis is a relatively common condition of the eye that can be caused by a number of different pathogens including bacteria and viruses. Clinical differentiation between adenoviral and bacterial conjunctivitis is difficult, often resulting in misdiagnosis and the provision of inappropriate treatment. METHODS A cost-effectiveness analysis was performed from a societal perspe...

Paired gonococcal isolates from 38 patients with recurrent episodes of gonorrhoea at varying intervals were examined for similarity by means of gonococcal auxotyping and susceptibility to antibiotics. A different gonococcal strain was the cause of the second infection in 53% of the patients. Longer intervals between infections were significantly associated with greater numbers of dissimilar str...

BACKGROUND AND OBJECTIVES Gonococcal fluoroquinolone resistance is now a significant problem in Japan. We generated gonococcal mutants resistant to norfloxacin in vitro from norfloxacin sensitive isolates and analysed the contribution of three known mechanisms of quinolone resistance in Neisseria gonorrhoeae. MATERIALS AND METHODS Three clinical isolates of N gonorrhoeae susceptible to norflo...

BACKGROUND & OBJECTIVE objectives: As antimicrobial susceptibility testing of Neisseria gonorrhoeae provides guidance for appropriate treatment, there is a need for simple, reliable and cost-effective method for susceptibility testing. The present study was aimed to compare the results of two methods of susceptibility testing, minimum inhibitory concentration (MIC) values by E test with disc di...

Pacific Region Gonococcal Surveillance Programme. 1994 Annual report. Comm Dis Intell 1995;19:495-499. 5. The World Health Organization Western Pacific Region Gonococcal Antimicrobial Surveillance Programme. Antimicrobial resistance in gonococci, Western Pacific Region, 1995. Comm Dis Intell 1996;20:425-428. 6. The World Health Organization Western Pacific Region Gonococcal Antimicrobial Survei...

5-iodo-2'-deoxyuridine (5IDU) is an antiviral compound which has a chemical composition closely resembling that of thymidine; the antiviral effect is thought to be due to the metabolic antagonism to the uptake of thymidine in the deoxyribonucleic acid (DNA) molecule (Prusoff, 1959). This molecule combined with protein is the main composition of the herpes simplex virus, upon the metabolism of w...

The recent increase in some parts of London of syphilis acquired homosexually (Lancet, 1964; Brit. med. J7., 1967) has indicated that a drug of nontreponemicidal properties is to be preferred in the treatment of gonococcal proctitis in homosexual men. Septrin was considered as a potentially useful remedy in these circumstances. Though taken orally and so subject to error or misuse, it needs be ...

In May 2012, a Coxsackievirus A24 haemorrhagic conjunctivitis was diagnosed in Marseille, France, in a traveller returning from the Comoros Islands. This case allowed identification of the cause of an ongoing outbreak of haemorrhagic conjunctivitis in Indian Ocean Islands, illustrating that returning travellers may serve as sentinels for infectious diseases outbreaks in tropical areas where lab...

BACKGROUND The aim of the project is to retrospectively study the changes in bacterial pathogens in acute neonatal bacterial conjunctivitis from 2002 to 2016 in Southern China. The results may provide the guidance for drug choice for acute neonatal bacterial conjunctivitis. METHODS Secretion specimens for bacterial culture were taken from 485 cases with clinically diagnosed acute bacterial ne...

In this report, we describe the first three cases of Tsukamurella conjunctivitis in the literature. All three patients presented with congestion of one eye with small amounts of serous discharge for 1 to 2 days. All three recovered after 10 days of treatment with polymyxin B-neomycin or chloramphenicol eyedrops. Sequencing of the 16S rRNA genes of the three isolates recovered from the serous di...