Spindle cell carcinoma also known as sarcomatoid carcinoma is a rare highly aggressive tumor which is histologically different from squamous cell ca and mesenchymal cancers. Only hands full of cases have been reported in literature since 1957 and hence no proper treatment protocol has been devised yet. We present such a case of thirty-four-year-old female who presented with spindle cell carcino...

In this work, organized as a short review, we present some results obtained by applying the Monte Carlo techniques in the Intra-Operative Radiation Therapy (IORT). The electron beams generated by the NOVAC7 IORT accelerator have been simulated using BEAMnrc/EGSnrc Monte Carlo code, the dose distributions and water-to-air stopping power ratios being later calculated with the associated software ...

A 73-year-old woman ultimately proven to have perforated colorectal adenocarcinoma presented to the emergency department with cellulitis of the abdominal wall. This case illustrates the challenge of diagnosis and management of such patients. It demonstrates limitations of colonoscopy and the importance of computed tomography to diagnose and characterize the disease. The optimal strategy for per...

Inflammatory breast cancer (IBC) is a rare and aggressive subtype of locally advanced breast cancer (LABC). Its diagnosis is primarily clinical; however, a pathological confirmation of invasive cancer is required. Historically, IBC was a uniformly fatal disease. A major advance in the last three decades has been the introduction of a multidisciplinary approach to the management of this aggressi...

BACKGROUND Chondroblastomas are rare epiphyseal bone tumors. Very few cases with extra-cortical aggressive soft tissue invasion or metastasis are reported. CASE PRESENTATION We report a 28 year-old adult male who presented with a large swelling over the left shoulder region. Pre-operative imaging revealed a large tumor arising from upper end of humerus with extensive soft tissue involvement n...

Metastatic bone disease is a major contributor to the deterioration of the quality of life of patients with cancer; it causes pain, impending and actual pathological fractures, and loss of function and may also be associated with considerable metabolic alterations. Operative treatment may be required for an impending or existing fracture and intractable pain. The goals of surgery are to provide...

Background: Chondroblastomas are rare epiphyseal bone tumors. Very few cases of extra-cortical aggressive soft tissue invasion or metastasis are reported. Case presentation: We report a 28 year old adult male who presented with a large swelling over left shoulder region. Pre-operative imaging revealed a large tumor arising from upper end of humerus with extensive soft tissue involvement necessi...

OBJECTIVE Although adjuvant therapy after surgery for non-small cell lung cancer (NSCLC) has been reported to be ineffective, it has been recently reported in prospective randomised studies conducted by two different groups in Japan that oral administration of a 5-fluorouracil (5-FU) derivative drug, UFT (a combination drug of tegafur and uracil) can improve the post-operative survival [The Stu...

Orthopedic trainees are assessed during training regarding their use of radiological screening during operative procedures. The authors investigated whether orthopedic trainees' use of fluoroscopic screening during ankle fixation operations varied with the 2 variables of consultant supervision and trainee experience. Data from operative fixation of isolated Weber B ankle fractures were reviewed...