نتایج جستجو برای: onchocerciasis
تعداد نتایج: 1363 فیلتر نتایج به سال:
Based on the observation that the parasite Onchocerca volvulus selectively absorbs vitamin A from the host, and the known toxicity of vitamin A in higher concentration, it was hypothesized that dying microfilariae (mf) release their stores of vitamin A (retinoids) into the host circulation in toxic concentrations, inducing the signs and symptoms of onchocerciasis. We conducted a pilot study to ...
Onchocerciasis (river blindness) is a human disease caused by the filarial worm Onchocerca volvulus. Adult worms can live for over a decade in skin nodules of affected humans, releasing millions of microfilariae that cause debilitating itching and blindness [1]. An estimated 37 million people are infected [2], and there are 46,000 new cases of blindness annually (http://www.apoc.bf/). Internati...
BACKGROUND The abundance of onchocerciasis vectors affects the epidemiology of disease in Sudan, therefore, studies of vector dynamics are crucial for onchocerciasis control/elimination programs. This study aims to compare the relative abundance, monthly biting-rates (MBR) and hourly-based distribution of onchocerciasis vectors in Abu-Hamed and Galabat foci. These seasonally-based factors can b...
Since the first description of ocular onchocerciasis in Africa was published (Hissette, 1931) many records have been made of the ocular lesions (e.g. Bryant, 1935; Hissette, 1938; Toulant and Boithias, 1952a, 1952b, 1954; World Health Organization Regional Conference on Onchocerciasis, 1956). However, no detailed account has been written of the progress of ocular signs and visual acuity in an u...
BACKGROUND The African Programme for Onchocerciasis Control (APOC) was created in 1995 to establish community-directed treatment with ivermectin (CDTi) in order to control onchocerciasis as a public health problem in 20 African countries that had 80 % of the global disease burden. When research showed that CDTi may ultimately eliminate onchocerciasis infection, APOC was given in 2008 the additi...
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