Several sources of information suggest that human beings evolved on a diet with a ratio of omega-6 to omega-3 essential fatty acids (EFA) of 1 whereas in Western diets the ratio is 15/1–16.7/1. Western diets are deficient in omega-3 fatty acids, and have excessive amounts of omega-6 fatty acids compared with the diet on which human beings evolved and their genetic patterns were established. Exc...

Diabetic nephropathy is the leading cause of end-stage renal disease and is associated with an increased risk of cardiovascular events. Dietary omega-3 fatty acid (FA) has cardioprotective effect and is associated with a slower deterioration of albumin excretion in patients with diabetic nephropathy. In this study, we evaluated the effect of omega-3 FA on proteinuria in diabetic nephropathy pat...

As with traditional feed grains, the form in which flax seed is fed impacts egg production and hen performance (Choi et al. 1986, Vilarino et al. 1996). Flax seed form also affects the amount of omega-3 polyunsaturated fatty acid (PUFA) incorporated into the egg. Differences in the omega-3 content of eggs from laying hens fed whole versus milled flax seed have been reported, with many researche...

BACKGROUND This randomized controlled trial investigated the role of omega-3 supplementation on C5L2 gene expression in type 2 diabetics. METHODS Subjects in the omega-3 group received 4 g omega-3 per day and subjects in the placebo group took four capsules of placebo per day for 10 weeks. Gene expression was measured by RT- PCR at the beginning and end of the study. RESULTS The results of ...

The potential benefit of fish oil (omega-3 fatty acids) consumption to reduce cardiovascular disease (CVD) risk remains controversial. Some investigations report reduced CVD risk associated with fish or fish oil consumption while others report no benefit. This controversy is in part resolved when consideration is given to omega-3 blood levels in relation to CVD risk as well as blood levels achi...

INTRODUCTION Recent studies found omega-3 fatty acid deficiency in brain cell membranes of schizophrenic patients. Conventional antipsychotics have many adverse reactions. Safety, availability and low price made omega-3 as a potential supplement for treatment of these patients. This study investigated the efficacy of omega-3 fatty acid as add-on treatment in schizophrenia. MATERIALS & METHODS...

Cardiovascular diseases and cancers are leading causes of morbidity and mortality. Reducing dietary saturated fat and replacing it with polyunsaturated fat is still the main dietary strategy to prevent cardiovascular diseases, although major flaws have been reported in the analyses supporting this approach. Recent studies introducing the concept of myocardial preconditioning have opened new ave...

Omega-3 oil from fish can be stabilised against oxidation using a variety of microencapsulation technologies. Complex coacervation has been used and found to be commercially useful for fortifying foods and beverages with long-chain omega-3 containing oils. Here we report a comparative human bioavailability study of microencapsulated omega-3 fish oil and standard fish-oil soft-gel capsules. Phos...

Omega-3 fatty acids are the most widely used nonvitamin supplement in the United States by both adults and children. 1 We presently lack data from adequately powered controlled trials to say definitively whether omega-3 (n-3) fatty acids are efficacious as mono-therapy in the treatment of major depressive disorder (MDD). Data are inconclusive regarding their efficacy as adjunctive therapy in MD...