Several complications attributed with Herpes virus related infections and the emergence of drug resistant viruses prompt scientists to search for new drugs. Several terpenoids and coumarins have shown anti HSV effects while no sesquiterpene coumarin have been previously tested for HSV treatment. Three sesquiterpene coumarins [badrakemin acetate (1), kellerin (2) and samarcandin diasteromer (3) ...

BACKGROUND In some studies, gum-chewing was demonstrated to have a beneficial effect on resumption of bowel function; however, other contradictory findings in other studies refute the effects of gum-chewing on peristaltic movements and digestive system stimulation. In addition, most previous studies were after colorectal or gynecology surgery, whereas few reports focused on the effect of gum-ch...

he reduced daily usage of nicotine gum to 16, 12, and 5 pieces, respectively, while using 3, 7, and 14 pieces of placebo gum. During week 6, he used no nicotine gum intake and averaged 17 pieces of placebo gum per day. During week 7 the 19 pieces of gum he used were divided between placebo gum and bubble gum. By week 8 and at the six-month follow-up he was using only bubble gum. We confirmed th...

In the course of our ongoing search for new natural products as leads against protozoal diseases, the dichloromethane extract of Indian frankincense, the oleo-gum-resin obtained from Boswellia serrata, showed in vitro activity against Plasmodium falciparum. Bioactivity-guided fractionation led to the isolation of eight diterpenes: (1S,3E,7E,11R)-verticilla-3,7,12(18)-triene (1), cembrene A (2),...

We investigated brain electric field signatures of subjective feelings after chewing regular gum or gum base without flavor. 19-channel eyes-closed EEG from 20 healthy males before and after 5 minutes of chewing the two gum types in random sequence was source modeled in the frequency domain using the FFT-Dipole-Approximation. 3-dimensional brain locations and strengths (Global Field Power, GFP)...

Gum odina and various parts of the plant Odina wodier are traditionally used in Indian folk medicine. Here an effort was made to investigate the efficacy of gum odina as new pharmaceutical excipients, in particular, as an emulsifying agent. Primary emulsion was prepared using wet gum method taking oil: water: gum (4:2:1) with gum acacia powder as an emulsifying agent. This was used as a standar...