the cellular organization of the olfactory epithelium of puntius sarana (hamilton, 1822) was explored by means of optical and scanning electron microscopy. the oval shaped olfactory rosette was composed of 26-28 primary lamellae distributed from both sides of the central raphe. the sensory epithelium confined chiefly on the linguiform processes of the lamella and rest of the portion consisted o...

REM sleep behaviour disorder (RBD) and olfactory dysfunction are common and very early features of alpha-synucleinopathies, in particular Parkinson's disease. To investigate the hypothesis that these two clinical features in combination are an indicator of evolving alpha-synucleinopathy, olfactory function was assessed in RBD. We studied 30 patients (18 male, 12 female; mean age 48 +/- 14 years...

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We studied the contribution of the main olfactory system to mate recognition and sexual behavior in female mice. Female mice received an intranasal irrigation of either a zinc sulfate (ZnSO4) solution to destroy the main olfactory epithelium (MOE) or saline (SAL) to serve as control. ZnSO4-treated female mice were no longer able to reliably distinguish between volatile as well as nonvolatile od...

BACKGROUND The aim of the study was to investigate odor identification performance in patients one year after hospital admittance due to stroke. Predictors for olfactory dysfunction were investigated as well as self-reported olfactory function and pleasantness of olfactory items. METHODS A 1-year prospective study was performed. Stroke location, classification and comorbidities were registere...

Parkinson’s disease (PD) is known for its motor alterations, but the importance of non-motor symptoms (NMSs), such as olfactory dysfunction (OD), increasingly recognized. OD may manifest during prodromal period disease, even before appear. Therefore, it suggested that this symptom could be considered a marker PD. This article briefly describes PD, evolution knowledge about in prevalence NMS and...

This review intends to integrate recent data from the Drosophila olfactory system into an up-to-date account of the neuronal basis of olfaction. It focuses on (1) an electron microscopic study that mapped a large proportion of fruitfly olfactory sensilla, (2) large-scale electrophysiological recordings that allowed the classification of the odor response spectra of a complete set of sensilla, (...

Electro-olfactogram (EOG) represents the sum of generator potentials of olfactory receptor neurons in response to an olfactory stimulus. Although this measurement technique has been used extensively in animal research, its use in human olfaction research has been relatively limited. To understand the promises and limitations of this technique, this review provides an overview of the olfactory ...

Neuronal activity is characterized by a diversity of oscillatory phenomena that are associated with multiple behavioral and cognitive processes, yet the functional consequences of these oscillations are not fully understood. Our aim was to determine whether and how these different oscillatory activities affect short-term synaptic plasticity (STP), using the olfactory system as a model. In respo...

Smell loss originates from peripheral disorders, like intranasal obstruction and olfactory cell injury, as well as central pathway diseases. Information derived from electrophysiological and psychophysical tests are useful for identifying loss of smell, but not for discriminating between central and peripheral deficits. This is because conventional imaging modalities are unable to deliver infor...