PURPOSE To determine the prevalence and clinical characteristics of trigeminal-cervical (TC) ocular referred pain. METHODS A retrospective study of 1,680 patients seen during 2002-2010 was performed in an ocular surface specialty center to identify patients with or without TC pain defined as ocular pain with ipsilateral trigger points located at the occipital region. Patients with refractory ...

in order to achieve prolong corneal contact time of norfloxacin(nfx) for treatment of extra ocular diseases, a ph triggered nanoparticulate in situ gelling system was designed to explore dual advantage of nanoparticles and in situ gelling system, for its ocular delivery. nfx loaded nanocarriers were developed by ionotropic gelation technique using chitosan as a matrix forming polymer, cross-lin...

A community based retrospective study was conducted in the satellite clinic of Nepal Medical College Teaching Hospital at Jhaukhel VDC of Bhaktapur, from March 2007 to February 2008. A total of 395 patients were examined, where males comprised of 135 patients (32.9%) and females 265 patients (67.1%). The common ocular diseases observed in this study were refractive errors 22.5%, age related cat...

Mouse models provide a valuable tool for exploring pathogenic mechanisms underlying inherited human disease. Here, we describe seven mouse models identified through the Translational Vision Research Models (TVRM) program, each carrying a new allele of a gene previously linked to retinal developmental and/or degenerative disease. The mutations include four alleles of three genes linked to human ...

The role of immuno-inflammatory responses in the cornea and ocular surface has continuously been evolving over the past decades and has been becoming the center stage for therapeutic approaches for many diseases. In fact, the relevance of inflammation as a significant component in the pathophysiology of most acute and chronic forms of corneal and ocular surface diseases (e.g., microbial keratit...

Ocular parasitosis in human is more prevalent in geographical areas where environmental factors and poor sanitary conditions favor the parasitism between man and animals. Lesions in the eye can be due to damage directly caused by the infectious pathogen, indirect pathology caused by toxic products, or the immune response incited by infections or ectopic parasitism. The epidemiology of parasitic...