Systematic differences in circadian rhythmicity are thought to be a substantial factor determining inter-individual differences in fatigue and cognitive performance. The synchronicity effect (when time of testing coincides with the respective circadian peak period) seems to play an important role. Eye movements have been shown to be a reliable indicator of fatigue due to sleep deprivation or ti...

We studied the role of eye dominance in non-rivalry conditions, testing dichoptic visual search and comparing performance with target presented to the dominant or non-dominant eye. Using red-green glasses, subjects viewed an array of green and red lines of uniform orientation, with a differently oriented target line present on half the trials. Performance was significantly better when the domin...

Darier-White disease (also known as Darier disease or keratosis follicularis spinulosa decalvans) is a rare dominantly inherited skin disorder characterized by firm, scaly, cutaneous papules and plaques distributed over various regions of the body. Histopathologic and electron microscopic studies of biopsied skin specimens have revealed a loss of cell to cell adhesion and abnormal differentiati...

congenital ocular motor apraxia (COMA), is characterized by the inability to initiate horizontal saccades on command with preserved vertical eye movements and generally preserved smooth ocular pursuit.1,2 Random spontaneous saccades may be seen in some patients with ISID. Although the term ‘congenital ocular motor apraxia’ is commonly used in the medical literature, it is inaccurate because the...

A three-year prospective, longitudinal, multi-school study was undertaken to investigate if either handedness, eyedness, their same or opposite side status (unilateral or crossed hand-eye dominance) was related to specific aspects of elementary school academic performance. Some 540 subjects, in 1 through 5 grades comprised the initial group. Testing on the reading sub-test of the Iowa Test of B...

LEOPARD syndrome (LS) is a congenital developmental disorder and is an acronym for multiple lentigines, electrocardiographic conduction abnormalities, ocular hypertelorism, pulmonary stenosis, abnormalities of genitalia, retardation of growth, and sensorineural deafness (1). These clinical features overlap those of Noonan syndrome (NS), and heterozygous germline PTPN11 mutations have been ident...

OBJECTIVES To describe new ocular findings associated with oculodentodigital dysplasia (ODDD) and a novel mutation in the connexin 43 transmembrane domain. DESIGN Oculodentodigital dysplasia is a rare autosomal dominant disease characterized by multiple systemic abnormalities, most commonly of the ocular, nasal, dental, and limb structures. Herein, we studied 2 patients with ODDD. We describe...

We studied the eye movements of several members of a family of Belgian sheepdogs that includes achiasmatic mutants. Our aim was to identify the types of nystagmus and other ocular motor abnormalities exhibited by the mutants. We also recorded from several unaffected heterozygous carriers of the genetic mutation and from a normal Irish Setter. Mutant dogs exhibited nystagmus waveforms that were ...

Ocular fundus fluorescein angiography was performed on 26 divers, who had used safe diving practices for at least 10 years, and on seven controls. There was no significant difference in the incidence of macular abnormalities between these groups and those of a previous study. Adherence to safe diving practice confers some protection against the macular abnormalities known to occur in divers wit...