the purpose of this study was to evaluate the probable effects of leptin addition in different levels to the semen extender on sperm quality (motility and motility parameters, viability, sperm membrane integrity, and dna damage). semen specimens were evaluated immediately after leptin addition, equilibration time and after thawing the frozen semen. five healthy buffalo bulls (5 ejaculates from ...

Reactive oxygen species (ROS) operate as key regulators of cellular homeostasis within a physiological range concentrations, yet they turn into cytotoxic entities when their levels exceed threshold limit. Accordingly, ROS are an important etiological cue for obesity, which in represents major risk factor multiple diseases, including diabetes, cardiovascular disorders, non-alcoholic fatty liver ...

This study attempted to clarify the relationship between the levels of 70kDa heat shock protein (HSP70) and semen quality in boars. Semen samples from 29 (13 Duroc, 9 Landrace, and 7 Yorkshire) boars (mean age=25.2+/-2.2 months) were examined. Three to four ejaculates per boar, collected during cool and hot seasons, were evaluated in terms of the sperm concentration, sperm motility, percentage ...

Background: Zinc in human semen seems to play an important role in the physiology of spermatozoa. Zinc deficiency leads to gonadal dysfunction, decreases testicular weight, and causes shrinkage of seminiferous tubules. The adult human body contains 1-3 g of zinc, about 0.1% of which is replenished daily. Excessively high amounts of zinc has been reported in human seminal plasma by many authors,...

Recent studies identified the presence of a male polycystic ovarian syndrome (PCOS), which mainly affects men whose female relatives are afflicted with PCOS, caused by genes responsible for the susceptibility of this syndrome in women. Similar hormonal, metabolic, and clinical alterations occurring in PCOS women have also been reported in their male relatives, suggesting a association between t...

Vitamin D levels have been linked to various health outcomes including reproductive disorders. The purpose of this study was to explore the association between serum vitamin D level (25-hydroxy-vitamin D, or 25OHD) and semen and hormonal parameters. This is a cross-sectional study that included 170 healthy men recruited for the study of spermatogenesis from the general population. Men completed...

The imbalance between energy intake and expenditure accompanied by the collapse of mechanisms protecting against the excessive accumulation of energy reserves are considered to be the main causes of obesity [1]. Accordingly, available treatments of obesity are aimed at decreasing calorie intake and/or increasing energy expenditure. However, long-term effects of various non-invasive methods incl...

Background: One of the most conventional causes of male infertility is increasing age, which has significant effects on sperm physiology. In advanced ages, degenerative alterations in germinal epithelium, decreased number of Leydig cells, and their functions affect spermatogenesis through a decrease in testosterone level. So it is important to know whether advanced paternal age is associated wi...