in the present study solid dispersions of the antifungal drug ketoconazole were prepared with pluronic f-127 and pvp k-30 with an intention to improve its dissolution properties. investigations of the properties of the dispersions were performed using release studies, differential scanning calorimetery (dsc), x-ray powder diffraction (xrd) and fourier transform infrared (ftir). the results obta...

bachground: endometriosis is a disease of female genital system, which is defined by the presence of ectopic endometrial tissue outside the uterine cavity. il-8 is an autocrine growth factor in the endometrium that contributes to the pathogenesis of endometriosis. the aim of this study was to investigate the association between -251t/a polymorphism in the il-8 gene and endometriosis risk in ira...

incorporation of [fe(bipy)cl4][bipy.h] (1) (where bipy is 2,2′-bipyridine) in the molecular sieves of the type lta, nay and mesoporous al-mcm-41 by using a “ship in a bottle synthesis” approach was investigated. [fe(bipy)cl4][bipy.h] was successfullyincorporated in the channels ofmesoporousal-mcm-41, and the product was characterized by x-ray diffraction, ftir and bet analysis. it was fou...

a facile and efficient method for the preparation of 1, 1-diacetates of aldehydes is improved.p2o5/sio2 catalyzed 1, 1-diacetates formation from aldehydes in dry media. advantages of this methodare the use of an inexpensive and selective catalyst with high yields in simple operation and shortreaction time under solvent-free conditions.

retention behavior of molecules mostly depends on their chemical structure. retention data of biologically active molecules could be an indirect relationship between their structure and biological or pharmacological activity, since the molecular structure affects their behavior in all pharmacokinetic stages. in the present paper, retention parameters (rm0) of biologically active 1,2-o-isopropyl...

our aim in this work is the synthesis and study optical and structural properties of gold nanoparticles.gold (iii) chloride trihydratewas taken as metal precursor, ascorbic acid at the presence of an appropriate amount of naoh as reducing agent and polyvinylpyrrolidonek-30 (pvp k-30) as a stabilizing and capping agent. the reaction was performed in high-speed stirring rate at room temperature.s...

background: viscerotropic leishmaniasis caused by leishmania tropica poses a significant prob­lem in the diagnosis and treatment management. since differential gene expression is more im­portant in outcome of the infection, we employed proteomic approach to identify potential pro­teins involved in visceralization of l. tropica . methods: the proteomes profiling of l. tropica isolated from cutan...

conclusions vaccine based on the conjugation of p. aeruginosa pao-1 lps with dt increased anti-lps antibodies and had a significant potential to protect against pseudomonas infections. background treatment of pseudomonas aeruginosa pao-1 infections through immunological means has been proved to be efficient and protective. objectives the purpose of this study was to produce a conjugate vaccine ...