abstract the objective of present study was to evaluate pharmacokinetic parameters of dibudipine phytosolve after oral administration in rats. the solubility test was carried out to select suitable oily solvent for dibudipine. phytosolve formulation was prepared with a medium chain triglyceride (mct) oil (20%), soybean phospholipids (5%) and a 70% fructose solution (75%). the effect of polyol c...

Societal Impact Statement Sorghum is an important cereal crop that provides calories and nutrients for much of the world's population, it often grown with low fertiliser input. Optimising yield, nutritive content bioavailability sorghum grain minimal input importance human nutrition, arbuscular mycorrhizal (AM) fungi have previously shown potential to assist in this. Across genetic diversity, A...

This work was aimed at evaluating the relative merits of bioaugmentation, biostimulation and surfactant-enhanced bioavailability of a desert soil contaminated by crude oil through biopile treatment. The results show that the desert soil required bioaugmentation and biostimulation for bioremediation of crude oil. The bioaugmented biopile system led to a total petroleum hydrocarbon (TPH) reductio...

Biological productivity in many ocean regions is controlled by the availability of the nutrient phosphorus. In the Mediterranean Sea, aerosol deposition is a key source of phosphorus and understanding its composition is critical for determining its potential bioavailability. Aerosol phosphorus was investigated in European and North African air masses using phosphorus near-edge X-ray fluorescenc...

An accumulating body of epidemiologic data, clinical trials, and mechanistic studies suggests that yogurt consumption as part of a healthy diet may be beneficial to cardiometabolic health. This brief review focuses on children and adolescents, introducing new concepts underlying the effect of yogurt consumption on body weight maintenance and the prevention of cardiovascular diseases. Specific p...

Sirtuins represent a novel family of enzymes that are collectively well situated to help regulate nutrient sensing and utilization, metabolic rate and ultimately metabolic disease. Activation of one of these enzymes, SIRT1, leads to enhanced activity of multiple proteins, including peroxisome-proliferator activated receptor coactivator-1alpha (PGC-1alpha), which helps to mediate some of the in ...

Understanding and improving environmental quality by reducing soil nutrient leaching losses, reducing bioavailability of environmental contaminants, sequestering C, reducing greenhouse gas emissions, and enhancing crop productivity in highly weathered or degraded soils, has been the goal of agroecosystem researchers and producers for years. Biochar, produced by pyrolysis of biomass, may help at...

Candida albicans is an opportunistic pathogen that causes candidiasis in humans. In recent years, metabolic pathways in C. albicans have been explored as potential antifungal targets to treat candidiasis. The glyoxylate cycle, which enables C. albicans to survive in nutrient-limited host niches and its. Key enzymes (e.g., isocitrate lyase (ICL1), are particularly attractive antifungal targets f...

The bioavailability of nutrients in sediments is one of the most important factors controlling ecological and physiological processes in the mangrove ecosystem (Alongi et al. 2002; Feller et al. 2002; Cheeseman & Lovelock 2004; Krauss et al. 2008). Although mangroves are highly productive, they are generally nutrient-deficient, relying on microbial and plant cycling processes for nutrients (Hol...